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Objectives: The aim of this scoping review was to summarize and discuss the direct resin composites used to reconstruct decayed molars with minimal class II cavities as described in the literature.
Data: The study protocol has been registered on the Open Science Framework platform and can be accessed at the following link: https://doi.org/10.17605/OSF.IO/2D45H. This scoping review was developed according to the PRISMA-ScR guidelines.
Sources: A literature search of 3 electronic databases was performed in MEDLINE (PubMed), SCOPUS and EMBASE with the last search in March 2024. Study selection was completed by two reviewers independently using the collaboration software platform Covidence (Covidence systematic review software, Veritas Health Innovation, Melbourne, Australia).
Study Selection: Of 8591 studies initially identified, full-text analysis was conducted in 82 studies. Any prospective clinical study conducted in adults involving an evaluation of composites on decayed molars with at least one proximal surface affected was included. Finally, 23 studies were included in this analysis.
Conclusions: Clinical studies on decayed molars with class II cavities show that direct composites are reliable restorations over the long term. Success rates are excellent, even after several years. However, further clinical studies on severely decayed molars with one or more missing cusps are needed to evaluate the effectiveness of these materials in direct techniques for even more complex cases.
Clinical Significance: Direct resin composites are reliable materials for restoring decayed molars with Class II cavities.
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http://dx.doi.org/10.1016/j.jdent.2025.106064 | DOI Listing |
J Chem Phys
September 2025
Department of Chemistry Education and Graduate Department of Chemical Materials, Pusan National University, Busan 46241, Republic of Korea.
Alkali salt-doped ionic liquids are emerging as promising electrolyte systems for energy applications, owing to their excellent interfacial stability. To address their limited ionic conductivity, various strategies have been proposed, including modifying the ion solvation environment and enhancing the transport of selected ions (e.g.
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Radioisotope Centre POLATOM, National Centre for Nuclear Research, Andrzeja Sołatana 7, 05-400 Otwock, Poland.
Terbium-161 (T = 6.89 d) is a low-energy β emitter (β 460 and 522 keV). It also emits γ radiation (25.
View Article and Find Full Text PDFMol Pharm
September 2025
Department of Nuclear Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Republic of Korea.
Dimeric fibroblast activation protein inhibitor (FAPI) radioligands are promising candidates for theranostic applications because of their enhanced tumor uptake and prolonged retention compared to monomeric radioligands. Several linker strategies have been investigated to connect two FAPI motifs and a radiometal chelator in a dimer design. In this study, we report the development of a novel dimeric FAPI radioligand, [Ga]Ga-, which utilizes a triazine core as a trifunctional linker.
View Article and Find Full Text PDFPLoS One
September 2025
Faculty of Engineering, University of Nottingham, Nottingham, United Kingdom.
Biochar is a carbon-rich material produced via pyrolysis that is increasingly recognized for its role in carbon sequestration, particularly through its application in agriculture and materials. However, accurately predicting the long-term persistence of biochar in the environment remains challenging. While incubation trials have been widely used to assess biochar degradation, their extrapolation beyond centennial timescales is uncertain.
View Article and Find Full Text PDFAppl Radiat Isot
August 2025
Department of Radiology, Washington University School of Medicine, Saint Louis, Missouri, 63110, United States. Electronic address:
We report a reliable fully automated procedure to produce a promising F-18 labeled sphingosine-1-phosphate receptor 1 (S1PR1) PET ligand, 3-((2-fluoro-4-(5-(4-(2-(fluoro-F)ethoxy)-3-(trifluoromethyl)phenyl)-1,2,4-oxadiazol-3-yl)benzyl) (methyl)amino)propan-1-ol ([F]FZTA) on the GE TRACERlab FX2N module, using a one-pot two-step procedure following current Good Manufacturing Practices (cGMP). The MOM-protected precursor 1 was fluorinated with no-carrier-added [F]KF, catalyzed by Kryptofix 222 under heat, to afford the intermediate [F]2. After deprotecting the MOM-group on [F]2 under acidic condition, the reaction was quenched into a neutralized solution, which was then loaded on semi-preparative HPLC for purification.
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