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Treatment options for mitral regurgitation (MR) have markedly evolved over the past few decades, with mitral valve transcatheter edge-to-edge repair (M-TEER) expanding the clinical armamentarium of guideline-directed medical therapy and surgical techniques. However, the variety of mitral valve anatomies, the presence of heart failure (HF), and consideration of the individual patient risk require a multidisciplinary Heart Team approach to identify the optimal treatment for MR for each patient. Despite the growing field of transcatheter mitral interventions and the longstanding availability of surgical mitral valve repair and replacement, evidence from randomized clinical trials comparing intervention with surgery remains scarce. In the meantime, the increasing safety and experience of surgical and interventional procedures have shifted the perspective on mitral valve disease in terms of when and how to treat it. Therefore, the multidisciplinary Heart Team discussion has become of paramount importance in the evaluation and treatment decisions for patients with mitral valve disease.
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http://dx.doi.org/10.1007/s00059-025-05328-8 | DOI Listing |
Multimed Man Cardiothorac Surg
September 2025
Department of Cardiothoracic Surgery, Royal Children’s Hospital, Melbourne, Australia
The patient had rheumatic heart disease, which resulted in severe aortic and mitral valve regurgitation. Repair of both valves was performed at 9 years of age. During surgery, the retracted aortic valve cusps required extension with bovine pericardial patches and suture reduction annuloplasty, and the mitral valve was repaired using a Cosgrove-Edwards (Edwards Lifesciences LLC, Irvine, CA) annuloplasty band.
View Article and Find Full Text PDFJ Thorac Cardiovasc Surg
September 2025
Division of Cardiac Surgery, Department of Surgery, Western University, London Health Science Centre, London, Ontario, Canada.
Cureus
August 2025
Acute Internal Medicine, University Hospitals of North Midland, Royal Stoke University Hospital, Stoke-on-Trent, GBR.
Infective endocarditis is a potentially fatal condition that can present with non-specific symptoms and rare hematologic manifestations, posing significant diagnostic challenges. We report a compelling case of a 67-year-old male with a history of type 2 diabetes, hypertension, and hyperlipidemia who sought medical attention for a five-month history of progressive iron deficiency anemia, accompanied by weight loss, fatigue, and vague constitutional symptoms. Initial extensive workup, including computed tomography of the thorax, abdomen, and pelvis, gastroscopy, colonoscopy, and transthoracic echocardiography, failed to identify an underlying cause.
View Article and Find Full Text PDFInt J Cardiol Heart Vasc
October 2025
Department of Cardiothoracic Surgery, Friedrich-Schiller-University Jena, University Hospital Jena, Germany.
Background: Cardiac biomarkers are important components for diagnosing perioperative myocardial infarction (MI). Efforts to detect MI by biomarker-release only faced heavy criticism, because cardiac biomarker-release has also been observed in situations that are not always related to cell death (e.g.
View Article and Find Full Text PDFFront Cardiovasc Med
August 2025
Department of Cardiovascular Medicine, Fengxian Central Hospital, Shanghai, China.
Background: Arterial compliance is an independent predictor of diastolic dysfunction. Invasive catheterization can accurately reflect diastolic function. However, studies on the invasive assessment of diastolic function are currently limited.
View Article and Find Full Text PDF