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Purpose Of The Study: Fixation of osteochondral fragments is a relatively common procedure in pediatric orthopaedic surgery. This study analyzes clinical and MRI results of biodegradable MAGNEZIX® magnesium alloy implants used to fix osteochondral knee lesions in pediatric patients.
Material And Methods: 18 pediatric patients with unstable or displaced OCD lesions or osteochondral fractures were treated with MAGNEZIX® screws or pins. Clinical examinations were conducted at regular intervals, and the final clinical and MRI assessments were performed 24 months after surgery.
Results: The overall functional scores at 24 months were found to be good, with a VAS score of 1.22 points ± 1.83, Lysholm score of 87.61 points ± 11.31, and IKDC score of 76.94 points ± 10.85 for both groups. On MRI, 14 patients (77.78%) showed complete union, four patients (22.22%) showed incomplete union, and none of the patients experienced healing failure. Complete implant absorption was examined in eight patients (44.44%) on MRI. Most patients exhibited varying degrees of chondropathy, and one patient required reoperation due to screw breakage and migration.
Conclusions: The use of MAGNEZIX® implants in the treatment of pediatric osteochondral fractures and OCD lesions has shown good clinical outcomes and favorable healing of osteochondral lesions. However, varying degrees of chondropathy have been observed in most cases.
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http://dx.doi.org/10.55095/achot2024/071 | DOI Listing |
J Appl Clin Med Phys
September 2025
Department of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia, USA.
Purpose: Real‑time magnetic resonance-guided radiation therapy (MRgRT) integrates MRI with a linear accelerator (Linac) for gating and adaptive radiotherapy, which requires robust image‑quality assurance over a large field of view (FOV). Specialized phantoms capable of accommodating this extensive FOV are therefore essential. This study compares the performance of four commercial MRI phantoms on a 0.
View Article and Find Full Text PDFJ Appl Clin Med Phys
September 2025
Icon Cancer Centre Toowoomba, Toowoomba, Queensland, Australia.
Introduction: The role of imaging in radiotherapy is becoming increasingly important. Verification of imaging parameters prior to treatment planning is essential for safe and effective clinical practice.
Methods: This study described the development and clinical implementation of ImageCompliance, an automated, GUI-based script designed to verify and enforce correct CT and MRI parameters during radiotherapy planning.
BMC Neurol
September 2025
Department of Neurology, University Hospital, RWTH Aachen University, Pauwelsstrasse 30, Aachen, North Rhine-Westphalia, Germany.
Background: Cerebellar pathologies in adults can have a wide range of hereditary, acquired and sporadic-degenerative causes. Due to the frequency in daily hospital, especially intensive care, settings, electrolyte imbalances are an important, yet rare differential diagnosis. The hypomagnesemia-induced cerebellar syndrome (HiCS) constitutes a relevant disease entity with clinical and morphological variability due to a potential progression of symptoms and a promising causal treatment.
View Article and Find Full Text PDFEur Radiol Exp
September 2025
Center for MR-Research, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.
Background: Fetal MRI is increasingly used to investigate fetal lung pathologies, and super-resolution (SR) algorithms could be a powerful clinical tool for this assessment. Our goal was to investigate whether SR reconstructions result in an improved agreement in lung volume measurements determined by different raters, also known as inter-rater reliability.
Materials And Methods: In this single-center retrospective study, fetal lung volumes calculated from both SR reconstructions and the original images were analyzed.
Mol Psychiatry
September 2025
Center for Depression, Anxiety and Stress Research, McLean Hospital, Belmont, MA, USA.
Dysregulated dopaminergic signaling has been implicated in the pathophysiology of major depressive disorder (MDD) and childhood sexual abuse (CSA), but inconsistencies abound. In a multimodal PET-functional MRI study, harnessing the highly selective tracer [C]altropane, we investigated dopamine transporter availability (DAT) and resting-state functional connectivity (rsFC) within reward-related regions among 112 unmedicated individuals (MDD: n = 37, MDD/CSA: n = 18; CSA no MDD: n = 14; controls: n = 43). Striatal DAT and seed-based rsFC were assessed in the dorsal and ventral striatum and the ventral tegmental area.
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