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Interatrial block (IAB) is a conduction disorder linked to atrial fibrillation (AF) and ischemic stroke. Intermittent IAB, often triggered by premature atrial complexes (PACs), may precede AF and increase thromboembolic risk. We present a case of embolic stroke of undetermined source (ESUS) with intermittent partial IAB detected on ECG. Serial ECGs and Holter monitoring were analyzed. Intermittent partial IAB with dynamic P-wave changes was observed. No AF or alternative embolic source was identified. Intermittent IAB may indicate atrial vulnerability in ESUS. Recognizing subtle ECG changes could aid risk stratification and stroke prevention.
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http://dx.doi.org/10.1111/anec.70109 | DOI Listing |
J Electrocardiol
September 2025
Department of Cardiology, Ankara City Hospital, Health Sciences University, Ankara, Turkey.
Background: Interatrial block (IAB) is an electrocardiographic manifestation of atrial conduction delay and structural remodeling. While it has been linked to atrial fibrillation (AF) and thromboembolic events, its potential role in predicting left atrial appendage (LAA) thrombus formation remains underexplored. This study aimed to investigate the association between IAB and the presence of LAA thrombus in patients with nonvalvular AF (NVAF) or atrial flutter referred for rhythm control procedures.
View Article and Find Full Text PDFHeart Rhythm
April 2025
Heart Center, Turku University Hospital and University of Turku, Turku, Finland. Electronic address:
Background: Various electrocardiographic P-wave indices are associated with cardiovascular comorbidities, such as atrial fibrillation (AF) and stroke. However, information on their stability is limited.
Objective: This study explored the prevalence and progression of P-wave abnormalities (PWAs) as well as their risk factors in an AF population.
Ann Noninvasive Electrocardiol
September 2025
Department of Cardiology, Necmettin Erbakan University, School of Medicine, Konya, Turkey.
Interatrial block (IAB) is a conduction disorder linked to atrial fibrillation (AF) and ischemic stroke. Intermittent IAB, often triggered by premature atrial complexes (PACs), may precede AF and increase thromboembolic risk. We present a case of embolic stroke of undetermined source (ESUS) with intermittent partial IAB detected on ECG.
View Article and Find Full Text PDFHeart Rhythm
July 2025
AIG Institute of Cardiac Sciences, Hyderabad, Telangana, India. Electronic address:
Background: Inter-atrial block (IAB) can contribute to the worsening of diastolic dysfunction in heart failure with preserved ejection fraction (HFpEF).
Objective: To determine the effects of accelerated Bachmann bundle area pacing (BBAP) in symptomatic patients with non-obstructive hypertrophic cardiomyopathy (nHCM), HFpEF, and IAB.
Methods: Prospective, randomized, patient-blinded crossover study in symptomatic patients with nHCM, HFpEF, and IAB.
JACC Case Rep
July 2025
Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta, Canada.
Background: Arrhythmogenic right ventricular cardiomyopathy (ARVC) has late clinical manifestations of right heart dysfunction, chamber dilation, and ventricular dysrhythmias. Elevated right-sided pressure and cardiac remodeling can result in late presentation of right to left interatrial shunting.
Case Summary: A 70-year-old man presented with ventricular tachycardia (VT) storm and significant hypoxemia.