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Psychological distress remains a significant public health concern, particularly among youth. With the growing integration of mobile and wearable technologies into daily life, digital phenotyping has emerged as a promising approach for early self-detection and intervention in psychological distress. The study aims to determine how behavioral and device-derived data can be used to identify early signs of emotional distress and to develop and evaluate a prototype system that enables users to self-detect these early warning signs, ultimately supporting early intervention and improved mental health outcomes. To achieve this, this study involved a multi-phase, mixed-method approach, combining literature review, system design, and user evaluation. It started with a scoping review to guide system design, followed by the design and development of a prototype system (ESFY) and a mixed-method evaluation to assess its feasibility and utility in detecting early signs of psychological distress through digital phenotyping. The results demonstrate the potential of digital phenotyping to support early self-detection for psychological distress while highlighting practical considerations for future deployment. The findings highlight the value of integrating active and passive data streams, prioritizing transparency and user empowerment, and designing adaptable systems that respond to the diverse needs and concerns of end users. The recommendations outlined in this study serve as a foundation for the continued development of scalable, trustworthy, and effective digital mental health solutions.
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http://dx.doi.org/10.3390/healthcare13162008 | DOI Listing |
JMIR Hum Factors
September 2025
KK Women's and Children's Hospital, Singapore, Singapore.
Background: Breast cancer treatment, particularly during the perioperative period, is often accompanied by significant psychological distress, including anxiety and uncertainty. Mobile health (mHealth) interventions have emerged as promising tools to provide timely psychosocial support through convenient, flexible, and personalized platforms. While research has explored the use of mHealth in breast cancer prevention, care management, and survivorship, few studies have examined patients' experiences with mobile interventions during the perioperative phase of breast cancer treatment.
View Article and Find Full Text PDFArch Gynecol Obstet
September 2025
Faculty of Medicine, University of Lille, 59000, Lille, France.
Purpose: Endometriosis is a chronic, hormone-dependent disease affecting up to 10% of women of reproductive age, often associated with chronic pelvic pain (CPP). Neuropathic pain has been increasingly recognized as a significant component in a subset of patients with CPP related to endometriosis. The study objective was to assess the prevalence of neuropathic-like pain in women with deep endometriosis (DE) and CPP, and to analyze its influence on pain perception and quality of life.
View Article and Find Full Text PDFA A Pract
September 2025
Department of Anesthesiology, Ospedale San Giovanni, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.
Childbirth-Related Posttraumatic Stress Disorder (CB-PTSD) can arise even after low-risk deliveries. This case report describes a 35-year-old woman who, despite a medically uncomplicated vaginal birth, developed severe CB-PTSD after being denied neuraxial analgesia and receiving remifentanil-PCA (remi-PCA) to manage pain. Her distress stemmed from inadequate pain relief, dissociation, and loss of control, exacerbated by unmet expectations for epidural analgesia.
View Article and Find Full Text PDFFront Oncol
August 2025
Health Management Department, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Background: Lung cancer remains a leading cause of cancer-related morbidity and mortality worldwide. As systemic therapy prolongs survival, improving patients' quality of life (QoL) has become a central goal of holistic care. Personalized nursing interventions, tailored to individual patient needs, have shown promise in oncology but lack large-scale evaluation in lung cancer populations.
View Article and Find Full Text PDFFront Neurosci
August 2025
Department of Medicine, Georgetown University Medical Center, Washington, DC, United States.
Introduction: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Gulf War Illness (GWI) have similar profiles of pain (nociception), visceral interoception, and tenderness (central sensitization) that may be due to dysfunction of midbrain and medulla descending antinociceptive and antiinteroceptive mechanisms. If so, then dolorimetry, a proxy for tenderness, may be correlated with subjective symptoms. The relationship with fatigue was assessed in Chronic Idiopathic Fatigue (CIF).
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