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Article Abstract
We report a RNA acylation strategy, namely, DNA-templated PNA-based RNA acylation, involving a DNA template and a peptide nucleic acid (PNA) strand. The DNA template is designed to hybridize with the accepting RNA and the donating PNA, so that the acyl group on the PNA is transferred to the 3'-end ribose hydroxyl group of the accepting RNA. This PNA system will provide a simple route for RNA acylation.
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| http://dx.doi.org/10.1021/acs.orglett.5c03169 | DOI Listing |
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