98%
921
2 minutes
20
Introduction: Incisional hernia (IH) remains a frequent and challenging postoperative complication, often requiring complex abdominal wall reconstruction (AWR). This study aimed to evaluate the outcomes of AWR and identify risk factors for wound complications and hernia recurrence at a district general hospital.
Methods: A retrospective cohort study was conducted at Queen's Hospital Burton, including 42 patients who underwent elective midline AWR between June 2017 and December 2023. Data on patient demographics, hernia characteristics, operative details, and postoperative outcomes were collected. Primary outcomes were hernia recurrence and wound complications. Secondary outcomes included hospital length of stay, postoperative ileus, fistula formation, and reoperation. Univariate statistical analysis was performed to identify predictors of wound complications; analysis for risk factors for recurrence was not feasible due to the low event rate.
Results: The mean patient age was 60.4 ± 12.5 years, with a mean BMI of 32.4 ± 5.0 kg/m². The most common repair technique was Rives-Stoppa, used in 28 (66%) patients. Hernia recurrence occurred in two (4.8%) patients, while wound complications were observed in 21 (50%) patients, predominantly seromas, which were noted in 12 (28.5%) patients. A BMI >35 kg/m² was significantly associated with wound complications (p=0.016). Other factors, including age, diabetes, smoking status, and hernia type, were not statistically significant predictors. The mean hospital stay was 5.4 ± 3.15 days, with a single postoperative mortality (2.4%). Conclusion: AWR using the Rives-Stoppa technique with retrorectus mesh placement resulted in low recurrence rates and acceptable morbidity, although postoperative wound complications occurred in half of the patients. High BMI was a significant predictor of wound complications. These findings underscore the importance of tailored surgical planning and preoperative optimization in high-risk patients undergoing complex ventral hernia repair.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12374597 | PMC |
http://dx.doi.org/10.7759/cureus.88565 | DOI Listing |
Diabetes Metab J
September 2025
Department of Vascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Background: Diabetic foot ulcer (DFU) represents a challenging complication of diabetes mellitus, characterized by slow healing processes. Protein kinase C delta (PKCδ) has been identified as a significant factor in the pathogenesis of various diabetic complications, including DFU. However, the precise underlying mechanisms remain to be fully elucidated.
View Article and Find Full Text PDFClin Anat
September 2025
Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
There are no standardized guidelines for reconstructive surgery of large temporal bone defects following lateral temporal bone resection for external auditory (acoustic) meatus carcinoma. Filling the defect with well-vascularized tissue is important for large tissue defects to promote wound healing and prevent infection postoperatively. Patients with malignant tumors of the external acoustic meatus requiring lateral temporal bone resection may sometimes necessitate postoperative adjuvant chemoradiotherapy.
View Article and Find Full Text PDFAm J Case Rep
September 2025
Department of Pediatrics, Southwest Healthcare Medical Education Consortium, Temecula, CA, USA.
BACKGROUND Morel-Lavallee lesions (MLLs) are uncommon, closed soft-tissue degloving injuries caused by high-energy trauma that are often missed due to their rarity and delayed presentation, resulting in serious complications. MLLs are particularly missed and underreported in pediatric and adolescent patients. We describe the case of an adolescent MLL occurring in an atypical lesion site at the calf to increase awareness of this diagnosis and associated presentation in this patient group, which can differ from adult presentation and contribute to diagnostic uncertainty that consequently impacts clinical decision-making.
View Article and Find Full Text PDFKorean J Physiol Pharmacol
September 2025
Department of Physiology & Medical Science, College of Medicine, Chungnam National University, Daejeon 35015, Korea.
Diabetes mellitus is a major global health concern associated with micro-and macrovascular complications. Among the diverse mechanisms that contribute to vascular dysfunction in diabetes, endothelial to mesenchymal transition (EndMT) has emerged as a key pathological process. EndMT involves the loss of endothelial cell characteristics and the acquisition of mesenchymal features, resulting in impaired endothelial function, increased fibrosis, and inflammation.
View Article and Find Full Text PDFClin Nucl Med
September 2025
Radiation Medicine Centre, Bhabha Atomic Research Centre, Tata Memorial Hospital Annexe, Parel.
Port site metastasis is an uncommon but clinically relevant complication, particularly associated with minimally invasive surgery for abdomino-pelvic malignancies, often indicating poor prognosis and necessitating prompt evaluation for potential surgical intervention. Proposed mechanisms include direct tumor implantation, aerosolization during pneumoperitoneum, surgical wound contamination, and immune alterations. In this report, we describe a case of a 48-year-old man who developed SSTR-expressing port site metastases, occurring 4 years and 4 months following laparoscopic resection of an ileal neuroendocrine tumor (NET).
View Article and Find Full Text PDF