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Background: Radon gas, a decay product of radium, is a significant environmental health risk due to its radioactive properties. Understanding the radium content and radon exhalation rates in soil is crucial for evaluating potential radiological hazards and ensuring environmental safety.
Methods: Soil samples were collected from twelve different locations in Wukro, Tigray, representing various soil types. The sealed can technique, using LR-115 Type-II plastic track detectors, was employed to measure radium concentrations and radon exhalation rates over a four-month exposure period. Radon mass exhalation rates, surface exhalation rates, and radium concentrations were calculated, and the Alpha Index was also determined to assess radiological risk.
Results And Discussion: The radon mass exhalation rates ranged from 0.18 × 10 Bq.kg .d to 0.82 × 10 Bq.kg .d , with a mean of 0.48 × 10 Bq.kg .d . Surface exhalation rates varied from 0.38 × 10 Bq.m .d to 1.72 × 10 Bq.m .d , averaging 1.02 × 10 Bq.m .d . Radium concentrations ranged from 0.33 to 1.47 Bq.kg , with an average of 0.87 Bq.kg . A significant positive correlation between radium content and radon exhalation rates was observed, indicating a direct relationship between these variables. Clay soils exhibited the highest radium concentrations, while sandy soils had the lowest. All measured values were below the safety limit of 370 Bq.kg recommended by OECD and UNSCEAR, suggesting no significant radiological risk in the study area.
Conclusion: This study highlights the importance of monitoring natural radiation levels for environmental safety. The findings provide a baseline for future studies and emphasize the need for continuous assessment to detect any long-term changes in soil radioactivity.
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http://dx.doi.org/10.12688/f1000research.160449.1 | DOI Listing |
Respir Med
September 2025
Scottish Centre for Respiratory Research, School of Medicine, University of Dundee, Dundee, United Kingdom. Electronic address:
Background: Eosinophilic chronic obstructive pulmonary disease (eCOPD), characterized by type 2 inflammation, is an emerging target for biologic therapies.
Objective: To indirectly compare the efficacy of dupilumab and mepolizumab in eCOPD, defined as blood eosinophil counts ≥300 cells/μL, by synthesizing data from phase 3 randomized controlled trials: BOREAS and NOTUS for dupilumab, MATINEE for mepolizumab.
Methods: We performed an indirect comparison of trial primary and secondary outcomes including annual exacerbation rates (AER), quality of life (St.
Sci Rep
September 2025
Federal Institute for Geosciences and Natural Resources (BGR), Stilleweg 2, 30655, Hannover, Germany.
The strategic importance of metals found in deep-sea polymetallic nodules has spurred a surge in interest for their exploitation. However, nodules are known to incorporate radionuclides during their growth, so that any industrial processing would involve classifying them as naturally occurring radioactive materials (NORM). As the start of deep-sea mining gets closer, concerns about elevated exposure to radiation that could result from the handling of nodules has recently been raised.
View Article and Find Full Text PDFGastroenterol Hepatol (N Y)
June 2025
Division of Gastroenterology, Mayo Clinic, Jacksonville, Florida.
Current screening methods for Barrett esophagus (BE), the precursor to esophageal adenocarcinoma (EAC), are inadequate with less than one-third of screen-eligible patients currently undergoing screening. In addition to low screening rates, key issues include overemphasis on gastroesophageal reflux disease symptoms and lack of provider awareness, owing in part to heterogeneous guidelines. To address these challenges, several new approaches are being explored: swallowable cell collection devices, exhaled volatile organic compounds analysis, blood-based molecular biomarkers, microbiome analysis, and alternative visualization methods such as transnasal and capsule endos-copy.
View Article and Find Full Text PDFChem Sci
August 2025
Tianjin Key Laboratory of Life and Health Detection, Life and Health Intelligent Research Institute, Tianjin University of Technology Tianjin 300384 P. R. China
Photoactivated sensors offer a safe, low-power alternative to thermal sensors, yet their performance against trace concentrations of weakly reactive biomarkers is fundamentally crippled by the rapid energy loss of photogenerated carriers electron relaxation into the band-edge. This process limits the number of electrons available for sensing. Here, we overcome this limitation by introducing a new principle: non-equilibrium hot-electron-mediated chemoresistance.
View Article and Find Full Text PDFFront Pharmacol
August 2025
Department of Physiology, College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
Type 2 (T2) inflammation underlies a substantial subset of moderate-to-severe asthma, contributing to persistent symptoms and frequent exacerbations. Dupilumab, a fully human immunoglobulin G subclass 4 (IgG4) monoclonal antibody, targets the interleukin-4 receptor alpha (IL-4Rα), thereby inhibiting both interleukin-4 (IL-4) and interleukin-13 (IL-13) signaling-which are key cytokines driving T2 inflammation. This review examines the formulation, pharmacological profile, clinical efficacy, safety, and cost-effectiveness of dupilumab in the treatment of asthma, with an emphasis on its role across T2-high and selected T2-low phenotypes.
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