Collision tumor of thyroid: A case report of synchronous papillary and follicular thyroid carcinoma.

Medicine (Baltimore)

Department of Surgery, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Gyeonggi-do, Korea.

Published: August 2025


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Article Abstract

Rationale: Collision tumors involving differentiated thyroid carcinomas are exceedingly rare, despite the overall high prevalence of thyroid cancer.

Patient Concerns: A 65-year-old man was incidentally diagnosed with thyroid cancer during a staging workup for gastric cancer.

Diagnoses: The histopathologic examination revealed 2 coincident cancers of the left thyroid lobe: papillary carcinoma (pT1bN1a) and follicular carcinoma (pT2N0).

Interventions: The patient underwent total thyroidectomy with central lymph node dissection, followed by thyroid hormone suppression and radioactive iodine therapy.

Outcomes: No postoperative complications or cancer recurrence has been observed to date.

Lessons: This case highlights the diagnostic challenges and surgical considerations associated with collision tumors of the thyroid. Appropriate management remains controversial; therefore, further case studies and consensus guidelines are necessary.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12385067PMC
http://dx.doi.org/10.1097/MD.0000000000043982DOI Listing

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