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Background: The robotic NICE procedure (Natural Orifice IntraCorporeal Anastomosis with Transrectal Extraction) has emerged as an innovative approach for left-sided colorectal resections. In this procedure, specimen extraction and completion of anastomosis are performed without abdominal wall incision, improving patient outcomes and potentially reducing healthcare costs.
Objective: This study aims to evaluate the cost-effectiveness of the robotic NICE procedure compared to open, laparoscopic, and robotic surgical approaches for left-sided colorectal resections.
Methods: This retrospective cohort study analyzed 351 patients who underwent elective, non-emergent left-sided colorectal resections between January 2018 and August 2021. Patients were grouped by surgical approach: open, laparoscopic, robotic, and robotic NICE. Generalized linear models were used to assess factors influencing direct and total costs.
Results: Among 351 patients, the robotic NICE procedure was associated with the lowest costs. The median direct cost for NICE was $9,946, which was significantly lower than laparoscopic ($16,389), robotic ($14,473), and open surgery ($10,427). The median total cost was also the lowest, at $22,263, compared to laparoscopic ($29,324), robotic ($32,908), and open surgery ($22,915). In adjusted analysis, compared to laparoscopic surgery, the NICE approach resulted in $5,736 in reduced direct costs and $6,393 in total costs, representing the largest cost savings across all comparisons. Patients with complications incurred an additional $4,519 in direct costs and $10,851 in total costs. Higher ASA grade increased direct costs by $1,976 and total costs by $4,242.
Conclusion: The robotic NICE procedure shows potential cost benefits by reducing direct expenses and improving patient outcomes. However, these findings should be interpreted cautiously, as institutional efficiencies and surgical expertise may influence cost differences.
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http://dx.doi.org/10.1007/s00464-025-12050-3 | DOI Listing |
Acta Neurochir (Wien)
September 2025
Gui de Chauliac Hospital, Montpellier University Medical Center, Montpellier, France.
Background: Awake surgery is the reference for diffuse low-grade glioma resection, allowing maximal tumor removal while preserving neurocognitive functions. It is also applicable to other brain tumors. However, key technical elements must be followed to ensure optimal conditions for intraoperative cognitive testing and reliable functional mapping.
View Article and Find Full Text PDFEur J Health Econ
September 2025
Erasmus School of Health Policy & Management, Erasmus University Rotterdam, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands.
Background: Policymakers face challenges in developing pricing policies for potentially innovative healthcare technologies (pIHTs) that balance limited budgets, access, and incentives for innovation. This study aimed to map existing evidence and identify knowledge gaps regarding price determinants and pricing policies for pIHTs and their effect on access and sustainability.
Methods: We conducted a scoping Review of scientific and grey literature in English published between 2014 and September 2023 with pre-specified inclusion and exclusion criteria to identify stakeholder-informed price determinants, pricing policies applied by European Economic Area (EEA) or Organisation for Economic Cooperation and Development (OECD) member states, and their access-related impacts.
Pediatr Blood Cancer
September 2025
Department of Radiation Oncology, Centre Léon Bérard, Lyon, France.
Background And Purpose: Ewing sarcoma (ES) is the most prevalent malignant thoracic tumor in childhood and young adults. This study reports the outcome of a national cohort treated in an international prospective trial for a localized rib ES, with a long follow-up.
Material And Methods: All the patients treated in a prospective trial (December 1999-April 2013) were included.
Ann Dermatol Venereol
September 2025
Université Grenoble Alpes, Service de dermatologie, Centre Hospitalier Universitaire, Grenoble, France; UGA/Inserm U 1209/CNRS UMR 5309 Joint Research Center, Institute for Advanced Biosciences, 38700 La Tronche, France.
Background: COVID-19 pandemic had a variable impact on the severity of melanomas.
Objective: To assess the role of the COVID-19 pandemic in France on the severity of melanomas at initial diagnosis.
Methods: New melanoma cases recorded in the French RIC-Mel database were included in a retrospective study spanning three timeframes: pre-COVID (01/01/2018 to 03/16/2020), lockdown (03/17/2020 to 10/05/2020), and the COVID pandemic period (hereafter referred to as "COVID") (11/05/2020 to 30/09/2022).
Ulus Travma Acil Cerrahi Derg
September 2025
Department of Thoracic Surgery, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul-Türkiye.
Background: This study aims to evaluate the performance of ChatGPT-4o in thoracic trauma management by comparing its responses to established clinical guidelines.
Methods: Five major thoracic surgery guidelines were reviewed, including the Advanced Trauma Life Support (ATLS) Guidelines 2018, Eastern Association for the Surgery of Trauma (EAST) Guidelines 2020, Evaluation and management of traumatic pneumothorax: A Western Trauma Association critical decisions algorithm 2022, European Trauma Course (ETC) Guidelines 2016, and the National Institute for Health and Care Excellence (NICE) Guidelines for Trauma 2020. Fifty open-ended questions were developed based on these guidelines and submitted to ChatGPT-4o.