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Faecal contamination of sacral pressure ulcers occurs frequently, so, theoretically, faecal diversion using colostomies is a useful procedure. We retrospectively analysed the data of adult patients for whom colostomies were created to enhance wound healing and compared patients with sacral pressure ulcers who received colostomies and those who did not during the same period. Patients' characteristics analysed included age, gender, comorbidities, WBC count, serum CRP level and microbial profile (before creating colostomy). Additionally, we examined whether the wound was closed, the recurrence rate after wound closure, and mortality outcomes. Regression analysis indicated that colostomy creation was associated with fewer species of gut microbiota cultured and lower rates of wound dehiscence after closure; no association was found between colostomy and mortality. Colostomies help promote wound healing of sacral pressure ulcers after closure by eradicating wound infection, and do not increase patients' mortality rates.
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http://dx.doi.org/10.1111/iwj.70737 | DOI Listing |
J Wound Care
September 2025
Houston Methodist Willowbrook Hospital, Houston, TX, US.
Objective: Purified collagen matrix containing a broad-spectrum antimicrobial, polyhexamethylene biguanide (PuraPly Antimicrobial (PCMP); Organogenesis Inc., US) has been shown to be an effective adjunct in managing wounds of different aetiologies. The aim of this study was to show the clinical outcomes of PCMP in the management of pressure injuries (PIs) and its implication on healthcare.
View Article and Find Full Text PDFAdv Wound Care (New Rochelle)
September 2025
Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
This study aimed to evaluate the location-specific and time-sensitive trajectories of pressure injuries (PrIs) stages using real-world electronic health record (EHR) datasets. Using a dataset of 29,475 patients with records of PrIs documented from 2015 to 2023, we developed four PrI patient sub-cohorts with common PrI locations, including coccyx, buttocks, sacrum and heel. We estimated transition intensities between three PrI states: stage 1, stage 2, and a severe stage in each group.
View Article and Find Full Text PDFInt Wound J
September 2025
Division of Plastic Surgery, Department of Surgery, Zuoying Armed Forces General Hospital, Kaohsiung, Taiwan.
Faecal contamination of sacral pressure ulcers occurs frequently, so, theoretically, faecal diversion using colostomies is a useful procedure. We retrospectively analysed the data of adult patients for whom colostomies were created to enhance wound healing and compared patients with sacral pressure ulcers who received colostomies and those who did not during the same period. Patients' characteristics analysed included age, gender, comorbidities, WBC count, serum CRP level and microbial profile (before creating colostomy).
View Article and Find Full Text PDFFront Med (Lausanne)
August 2025
Department of Operating Room, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, China.
Background: Pressure injury prevention is clinically critical for optimizing patient outcomes. This meta-analysis systematically evaluates the efficacy of silicone foam dressings in preventing pressure injuries specifically in the sacral and heel regions.
Methods: A comprehensive literature search was conducted across PubMed, Embase, ClinicalTrials.
Geriatrics (Basel)
August 2025
College of Nursing & Research Institute of Nursing Science, Chungbuk National University, Cheongju 28644, Republic of Korea.
Background/objectives: Pressure injuries are a significant concern among older adults, particularly in community-based long-term care settings where prolonged immobility is prevalent. This study aimed to identify factors influencing sacral interface pressure in community-dwelling older adults, with an emphasis on support surface usage and clinical risk indicators.
Methods: A total of 210 participants aged 65 years and older, all receiving long-term care services in South Korea, were enrolled in this study.