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Background: It is difficult to achieve health related Sustainable Development Goals when a higher proportion of birth delivery occurs through cesarean section (CS) than vaginal delivery without considerable medical benefits. This study aims to identify the spatial hot spot clustering and determinants of cesarean section in northeastern states, India.
Methods: The study utilized data from the fifth round of the National Family Health Survey (NFHS-5, 2019-2021), which included responses from 34,222 mothers who delivered live births in the five years preceding the survey. The study investigated spatial hot spot clustering of CS prevalence using Getis-Ord Gi* statistics and applied multiscale geographically weighted regression (MGWR) to identify spatial clusters in the relationships between predictor variables and CS delivery.
Results: The study identified spatial hot spot clustering of CS rates in districts of Sikkim, western and southern Tripura, eastern and western Assam, and central Manipur. MGWR results indicated that significant determinants of CS include maternal age (30-49 years), first birth order, highest educational level, high body mass index, and highest wealth quintile, with regression coefficients varying significantly by district in this region.
Conclusion: The study found that CS rates vary by clusters in the districts of northeastern states of India. It suggests that piloting educational interventions for pregnant women and regularly monitoring CS facilities could be initial strategies to better understand and address the higher CS trends in these regions.
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http://dx.doi.org/10.1007/s13224-025-02150-4 | DOI Listing |
JMIR Public Health Surveill
September 2025
Department of Preventive Medicine, College of Medicine, Korea University, 73 Goryeodae-ro, Seoungbuk-gu, Seoul, 02841, Republic of Korea, 82 2-2286-1169.
Background: Scrub typhus (ST), also known as tsutsugamushi disease, is a common febrile vector-borne illness in South Korea, transmitted by trombiculid mites infected with Orientia tsutsugamushi, with rodents serving as the main hosts. Although vector-borne diseases like ST require both a One Health approach and a spatiotemporal perspective to fully understand their complex dynamics, previous studies have often lacked integrated analyses that simultaneously address disease dynamics, vectors, and environmental shifts.
Objective: We aimed to explore spatiotemporal trends, high-risk areas, and risk factors of ST by simultaneously incorporating host and environmental information.
Adv Mater
September 2025
Department of Engineering, School of Computing and Engineering, University of Huddersfield, Queensgate, Huddersfield, HD1 3DH, UK.
A new family of nanostructured ternary intermetallic compounds - named the ZIP phases - is introduced in this work. The ZIP phases exhibit dualistic atomic ordering, i.e.
View Article and Find Full Text PDFEnviron Monit Assess
September 2025
Indira Gandhi Conservation Monitoring Centre, World Wide Fund-India, New Delhi, 110003, India.
Understanding the intricate relationship between land use/land cover (LULC) transformations and land surface temperature (LST) is critical for sustainable urban planning. This study investigates the spatiotemporal dynamics of LULC and LST across Delhi, India, using thermal data from Landsat 7 (2001), Landsat 5 (2011) and Landsat 8 (2021) resampled to 30-m spatial resolution, during the peak summer month of May. The study aims to target three significant aspects: (i) to analyse and present LULC-LST dynamics across Delhi, (ii) to evaluate the implications of LST effects at the district level and (iii) to predict seasonal LST trends in 2041 for North Delhi district using the seasonal auto-regressive integrated moving average (SARIMA) time series model.
View Article and Find Full Text PDFMol Carcinog
September 2025
Department of Urology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
B cells located in tertiary lymphoid structures (TLSs) may undergo clonal expansion, somatic hypermutation, isotype switching, and tumor-specific antibody production, suggesting that antibody-producing plasma cells may be involved in antitumor immunity. This study used a combination of single-cell sequencing (five samples from our center, and four samples from PRJNA662018) and spatial transcriptome (one sample from our center, and four samples from GSE169379) research methods to investigate the relationship between TLSs and the immunoglobulin repertoire in muscle invasive bladder cancer (MIBC). 405 patients with MIBC from TCGA and 348 patients with metastatic urothelial carcinoma on PD-L1 inhibitor treatment from the IMvigor210 trial were included in this study.
View Article and Find Full Text PDFChem Sci
August 2025
Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University Hung Hom Hong Kong China
The development of high-performance near-ultraviolet organic light-emitting diodes (NUV-OLEDs) remains challenging due to their intrinsic wide-bandgap characteristics. Therefore, this study fully exploits the weak electron-accepting characteristics of the PPI group, combined with its high photoluminescence quantum yield (PLQY) and excellent thermal stability. Through a precise molecular structure modulation strategy involving direct introduction of electron-donating diphenylamine groups into the side phenyl ring and systematic integration of donor/acceptor units with tailored electronic properties into the main backbone, effective control of excited-state characteristics and their spatial distribution was successfully achieved.
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