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Although structural strategic family therapy (FT) is an evidence-based approach for adolescent behavior problems, manualized family therapy models have not been widely adopted in usual care due to the training and implementation resources required. This article presents a competency framework for utilizing family collaboration with adolescent cases. It begins by discussing challenges to implementing FT in routine care and presents the core elements strategy, then introduces three "branches" that together constitute a continuum of family involvement-family collaboration, family skills training, and systemic family therapy-and describes the rationale and procedures for focusing on competency guidelines for family collaboration specifically. It then describes the basic techniques and competency guidelines for six core elements of family collaboration: family systems outreach, adolescent ecosystem, location of self, goal setting, family participation, caregiver consultation, family session management. It concludes by discussing future directions for this framework and the development of additional competencies for the other branches. While further research is necessary to test the efficacy of the treatment branches and accompanying competency standards, this article presents an innovative approach to involving family members in care that includes accessible competency guidelines.
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http://dx.doi.org/10.1007/s10591-024-09696-x | DOI Listing |
Alzheimers Res Ther
September 2025
Department of Neurology, Saarland University, Kirrberger Straße, 66421, Homburg/Saar, Germany.
Background: Alzheimer's disease (AD) patients and animal models exhibit an altered gut microbiome that is associated with pathological changes in the brain. Intestinal miRNA enters bacteria and regulates bacterial metabolism and proliferation. This study aimed to investigate whether the manipulation of miRNA could alter the gut microbiome and AD pathologies.
View Article and Find Full Text PDFDiagn Pathol
September 2025
Department of Gastrointestinal Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
Background: Gastric cancer is one of the most common cancers worldwide, with its prognosis influenced by factors such as tumor clinical stage, histological type, and the patient's overall health. Recent studies highlight the critical role of lymphatic endothelial cells (LECs) in the tumor microenvironment. Perturbations in LEC function in gastric cancer, marked by aberrant activation or damage, disrupt lymphatic fluid dynamics and impede immune cell infiltration, thereby modulating tumor progression and patient prognosis.
View Article and Find Full Text PDFBMC Psychol
September 2025
Behavioral Epidemiology, Institute of Clinical Psychology and Psychotherapy, TUD Dresden University of Technology, Chemnitzer Straße 46, 01187, Dresden, Germany.
Background: Disruptive behavior and emotional problems - especially anxiety - are common in children and frequently co-occur. However, the role of co-occurring emotional problems in disruptive behavior intervention response is unclear. This study aimed to compare the effectiveness of an indicated prevention program in children with disruptive behavior problems with vs.
View Article and Find Full Text PDFGenome Biol
September 2025
Department of Evolutionary Genetics, Max-Planck Institute for Evolutionary Biology, Plön, Germany.
Background: Most RNA-seq datasets harbor genes with extreme expression levels in some samples. Such extreme outliers are usually treated as technical errors and are removed from the data before further statistical analysis. Here we focus on the patterns of such outlier gene expression to investigate whether they provide insights into the underlying biology.
View Article and Find Full Text PDFBMC Med Ethics
September 2025
Dept of Neurobiology, Care Sciences, and Society, Karolinska Institutet, Stockholm, Sweden.