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Objective: We illustrate transcatheter left atrial appendage closure under local anesthesia with intracardiac echocardiography guidance for a complex patient with repaired tetralogy of Fallot at high risk for general anesthesia, with preprocedural cardiac computed tomography (CT) support.
Key Steps: 1) CT imaging and analysis; 2) vascular access with use of sheath-in-sheath technique; 3) transseptal puncture with VersaCross system; and 4) deployment of Watchman device in CT-planned projection.
Potential Pitfalls: 1) Selection of appropriate preprocedural imaging modality; 2) use of sheath-in-sheath technique to avoid kinking of catheters; 3) use of VersaCross transseptal system to avoid repeat punctures, unnecessary exchanges, and risk of injury; and 4) avoidance of general anesthesia to reduce risk in a high-risk patient.
Take-home Messages: Preprocedural CT analysis and intraprocedural intracardiac echocardiography imaging can guide transcatheter left atrial appendage closure procedures in complex anatomies. The use of appropriate sheaths and equipment can improve the safety profile and success rate of complex transcatheter left atrial appendage closure procedures.
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http://dx.doi.org/10.1016/j.jaccas.2025.104644 | DOI Listing |
Prog Cardiovasc Dis
September 2025
Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH, USA. Electronic address:
Objectives: This study explores the impact of lower baseline aortic valve (AV) mean gradients on the clinical outcomes of patients with low-gradient aortic stenosis (LG AS) post-transcatheter aortic valve replacement (TAVR). Additionally, the study aims to understand the predictors of a lower baseline AV mean gradient (MG).
Background: Reduced left ventricular ejection fraction (LVEF) and low-flow states are known to correlate with worse clinical outcomes.
J Invasive Cardiol
September 2025
Newark Beth Israel Medical Center, Newark, New Jersey.
Objectives: The authors hypothesized that the origin of the right coronary artery (RCA) is a direct continuation of the major aortic arch branches (MAAB) takeoff plane, which may have implications for brachiocephalic interventions and next generation transcatheter aortic valve intervention (TAVI) embolic protection devices (EPDs).
Methods: In this single-center, retrospective, cross-sectional study, the authors analyzed computed tomographic angiography (CTA) images from 92 patients undergoing TAVI evaluation to determine the spatial relationship between the origin of the RCA and the MAAB takeoff plane. Patients with prior cardiothoracic or aortic interventions and those with anomalous RCA origin were excluded.
ESC Heart Fail
September 2025
Institute of Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.
Atrial functional mitral regurgitation (AFMR) is an increasingly recognized subtype of mitral regurgitation, characterized by left atrial remodelling and mitral annular dilation in the absence of primary mitral valve disease or left ventricular dysfunction. Closely linked to chronic atrial fibrillation and heart failure with preserved ejection fraction, AFMR is associated with poor clinical outcomes and represents a growing therapeutic challenge. This expert opinion paper summarizes current evidence on the epidemiology, pathophysiology, diagnosis and management strategies, including medical therapy and emerging data supporting surgical and transcatheter interventions in selected patients.
View Article and Find Full Text PDFEur Heart J Case Rep
September 2025
Department of Cardiology, Toyohashi Heart Center, 21-1 Gobutori, Oyamacho, Toyohashi 441-8530, Japan.
Background: Mitral regurgitation (MR) may rarely worsen after transcatheter aortic valve implantation (TAVI) due to mechanical interference from the transcatheter heart valve (THV). Standard surgical approaches in these cases are often challenging due to anatomical constraints. Thus, there is a need for the development of effective alternatives to address this issue.
View Article and Find Full Text PDFRev Cardiovasc Med
August 2025
Department of Cardiology, Harbin Medical University, 150000 Harbin, Heilongjiang, China.
Background: Differences between female and male patients may influence the outcomes of transcatheter aortic valve replacement (TAVR). However, knowledge regarding known sex differences in TAVR procedures among Chinese people remains limited. Therefore, this study aimed to investigate the impact of sex-related differences on reverse left ventricular (LV) remodeling following TAVR in the Chinese population.
View Article and Find Full Text PDF