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Overhead work poses a significant risk for shoulder musculoskeletal disorders due to elevated arm postures and sustained loading, yet current ergonomics tools provide limited guidance on the acceptable percentage of time such tasks can be performed. This concept, referred to as the Maximum Acceptable Duty Cycle (MADC), represents the proportion of time within a work cycle that an exertion can be sustained at a psychophysically acceptable level. This study addresses that gap by reconfiguring an existing ergonomics assessment tool for overhead work to estimate MADC, rather than maximum acceptable forces. MADC values across the overhead workspace were mapped using computational modeling of over 800,000 overhead hand positions under three superior-directed load conditions (5, 10, and 20 N). MADC varied substantially with hand position and force demand: at 5 N, values ranged from 0-40 %, while at 20 N, MADC never exceeded 14 %. A consistent ergonomic 'sweet spot' was identified slightly above and forward of the shoulder, where MADC is maximized, providing the largest design space for allowable task duty cycles. The reconfigured tool offers actionable, evidence-based guidance for overhead task design by informing duty cycle limits in industrial settings, where current one-size-fits-all thresholds lack empirical justification.
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http://dx.doi.org/10.1016/j.jelekin.2025.103049 | DOI Listing |
Beetroot ( L.) incorporation into cupcake formulations represents an innovative approach to developing functional bakery products that combine consumer appeal with enhanced nutritional value. This study investigated the incorporation of beetroot ( L.
View Article and Find Full Text PDFClin Pharmacol Drug Dev
September 2025
Phase I Clinical Research Centre, Wuhan Pulmonary Hospital, Wuhan, China.
Tamsulosin is a highly selective α1A adrenergic receptor antagonist that can relax smooth muscles in the urethra, bladder neck, and prostate and improve urinary disorders. It is therefore widely used to treat lower urinary tract symptoms caused by benign prostatic hyperplasia. The aim of this study is to evaluate the pharmacokinetic (PK) characteristics and bioequivalence of 2 different formulations (tamsulosin sustained-release tablets and tamsulosin sustained-release capsules) in healthy Chinese subjects.
View Article and Find Full Text PDFExplor Res Clin Soc Pharm
December 2025
Sydney Pharmacy School, Faculty of Medicine and Health, The University of Sydney, NSW, Australia.
Background: The emerging role of pharmacists in chronic kidney disease (CKD) care prompted the pharmacy-led screening and quality use of medicines in CKD trial (QUM-CKD), a pharmacy-led screening initiative to detect previously undiagnosed CKD and improve medication safety.Objective: To explore pharmacists' experiences and perspectives on the implementation of the QUM-CKD trial in Australian community pharmacies.
Methods: A descriptive phenomenological qualitative approach was employed, involving in-depth, semi-structured telephone interviews with thirteen metropolitan and rural community pharmacists in the trial.
Clin Pediatr (Phila)
September 2025
Department of Pediatrics, Columbia University Irving Medical Center, New York, NY, USA.
The adolescent mental health crisis is compounded by a shortage of mental health services, which mobile health apps may alleviate. We assessed the feasibility and acceptability of the Wysa app (a commercially available app containing cognitive behavioral therapy-based digital modules and an artificial intelligence-based conversational agent) among 13- to 18-year-old adolescents recruited from a primary care clinic in New York City and online from March to June 2022. We assessed adolescent engagement in the Wysa app over a 3-week period.
View Article and Find Full Text PDFJ Voice
September 2025
Research and Development, Complete Vocal Institute, Kompagnistraede 32A, 1208, Copenhagen K, Denmark. Electronic address:
Aims And Objectives: Primary muscle tension dysphonia (pMTD) is a common cause of voice disorders and is treated by speech and language pathologists (SLPs). Some singing teachers specializing in the habilitation of the performance voice also have rehabilitation skills helping singers recover from illness. The aim of this pilot study was to assess the feasibility and acceptability of using a structured and well-characterized habilitation and rehabilitation pedagogic technique for singers, The Complete Vocal Technique (CVT), in the treatment of patients with speaking voice problems due to pMTD.
View Article and Find Full Text PDF