Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Wastewater surveillance is a critical tool in responding to the COVID-19 pandemic, yet traditional centralized methods are unsustainable due to their high costs and complex implementation requirements. Here, we introduce Wastewater Analysis and Tracking for Epidemiological Recognition: Necessary Early Warning System (WATER NEWS)-a field clustered regularly interspaced short palindromic repeats-diagnostic approach designed for robust and cost-effective pathogen detection in wastewater treatment plants (WWTPs). WATER NEWS combined a one-pot assay, an optimized reporter probe, on-site nucleic acid extraction, an improved freeze-drying process and a user-friendly, low-cost, battery-operated device, thereby overcoming the limitations of field-deployable wastewater surveillance. In evaluations across 25 WWTPs in 10 Chinese cities, WATER NEWS achieved sensitivities exceeding 90% and specificities of 100% in SARS-CoV-2 detection from the influent and effluent samples of WWTPs. Notably, the system consistently detected SARS-CoV-2 presence within 20 days at a local WWTP. Economic analysis reveals that our approach achieved a 6.5-fold cost reduction compared with clinical testing and costs nearly half that of traditional wastewater surveillance methods, making it a viable and sustainable option for wastewater surveillance.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12365751 | PMC |
| http://dx.doi.org/10.1093/nsr/nwaf275 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Wastewater Monitoring: Improving Public Awareness and Understanding in the United States, May 2024.
Public Health Rep
September 2025
Brown School, Washington University, St. Louis, MO, USA.
Objectives: Although wastewater monitoring for virus detection has increased in communities worldwide, public awareness, understanding, questions, and concerns about wastewater monitoring are largely unknown. We assessed awareness, knowledge, and support for wastewater monitoring for detection of viruses and bacteria among US residents and elicited questions and concerns from residents about its use.
Methods: We conducted a survey among a racially and ethnically diverse sample of residents in Colorado, Maryland, Missouri, Nebraska, and Texas to assess awareness, knowledge, and support of wastewater monitoring.
Site-specific assessment of illicit drug consumption patterns in South Korea via wastewater-based epidemiology.
Water Res
August 2025
Department of Civil and Environmental Engineering, Pusan National University, Busan 46241, Republic of Korea; Institute for Environment and Energy, Pusan National University, Busan 46241, Republic of Korea. Electronic address:
Wastewater-based epidemiology (WBE) is increasingly used as a complementary tool for monitoring drug use at the population level, providing anonymized, real-time estimates of community drug consumption. Site-specific applications of WBE can identify localized patterns that national or municipal surveys may overlook. This study presents the first comprehensive, site-specific assessment of illicit drug use in South Korea using WBE.
View Article and Find Full Text PDFWastewater surveillance of SARS-CoV-2 and influenza in a dynamic university community: understanding how wastewater measurements correspond to reported cases.
Sci Total Environ
September 2025
Department of Biology, The Pennsylvania State University, University Park, PA 16802, USA; Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA 16801, USA. Electronic address:
Wastewater surveillance is increasingly an effective public health tool for responding to epidemics and preparing for annual cycles of respiratory illnesses. We measured genetic markers from Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), influenza A virus (IAV) and influenza B virus (IBV) in untreated wastewater of a university campus and its local residential community over a four-year period using digital Polymerase Chain Reaction (PCR) methods. These data were then analyzed and compared to clinical case data reported to the state by zip code.
View Article and Find Full Text PDFWhole-genome sequence of 19 , isolated from municipal wastewater in State College, Pennsylvania.
Microbiol Resour Announc
September 2025
Department of Food Science, The Pennsylvania State University, University Park, Pennsylvania, USA.
Eight wastewater samples were collected from three sites in State College, Pennsylvania, during June and July 2024. Nineteen were isolated and sequenced. Three isolates were ≤9 SNPs different from human cases deposited in GenBank, highlighting the potential for wastewater-based surveillance to monitor outbreaks.
View Article and Find Full Text PDFRespi-Radar: a tool to monitor respiratory infections, Belgium, winter season 2023/24.
Euro Surveill
September 2025
Crisis Preparedness and Response, Sciensano, Brussels, Belgium.
Following the experience gained during the COVID-19 pandemic, the Belgian Risk Assessment Group (RAG) developed the Respi-Radar in the summer of 2023 to assess the epidemiological situation of respiratory infections and inform public health preparedness and response in Belgium. The Respi-Radar consists of four risk levels (green, yellow, orange and red), which indicate the extent of viral circulation and/or pressure on the healthcare system. Based on these risk levels, authorities can apply adequate measures depending on the epidemiological trends.
View Article and Find Full Text PDF