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Objective: This study aimed to evaluate the psychometric function curve and signal-to-noise ratio (SNR) loss values during the "Vocale Rapide dans le Bruit" (VRB) speech-in-noise test with speech level presentations at 65dB SPL (VRB65) and 45dB SPL (VRB45) in normal-hearing subjects.
Materials And Methods: Adult normal-hearing subjects underwent an audiological evaluation including tympanometry, pure-tone audiometry, speech recognition threshold in silence and speech-in-noise audiometry following the recommended protocol (65dB SPL, VRB), followed by a second series of tests with a lower sentence presentation level (45dB SPL, VRB).
Results: Among the 29 normal-hearing subjects, there was no significant variation in the psychometric function curves or SNR loss values for VRB or VRB.
Conclusion: The "Vocale Rapide dans le Bruit" speech-in-noise test is a relevant tool for assessing auditory difficulties in noisy environments. In normal-hearing subjects, presenting sentences at different intensity levels did not show a significant difference. This was an essential prerequisite for its use at various signal presentation levels, which could enable the evaluation of the functional state of high- and low-threshold auditory nerve fibers. This, in turn, would refine clinical diagnosis and improve the management of hearing disorders associated with hidden hearing loss.
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http://dx.doi.org/10.1016/j.anorl.2025.06.008 | DOI Listing |
NIHR Open Res
September 2025
Department of Neurology, North Bristol NHS Trust, Westbury on Trym, England, UK.
Background: This study aimed to explore the barriers and facilitators of implementing rehabilitation interventions for visual field loss due to stroke.
Methods: The study was a qualitative exploration using one-to-one interviews coded using template analysis and the COM-B a-priori framework. Participants were five occupational therapists from hospital (n=4) and community (n=1) National Health Service (NHS) stroke care settings in England.
J Cachexia Sarcopenia Muscle
October 2025
Department of Surgery, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, the Netherlands.
Background: Body composition alterations such as skeletal muscle (SM) loss in cancer patients are associated with poor survival. In turn, immune cell-driven pathways have been linked to muscle wasting. We aimed to investigate the relationship between body composition, tumour-infiltrating lymphocytes and survival in patients with advanced lung cancer.
View Article and Find Full Text PDFJ Assist Reprod Genet
September 2025
UFR-SVS, UVSQ, 78180, Montigny Le Bretonneux, France.
Introduction: Complex chromosomal rearrangements (CCRs) are frequently associated with infertility and have been described in the literature. Chromoanagenesis corresponds to a group of CCRs with a high number of chromosome breakpoints. These CCRs involving small structural variations can only be identified by using high-resolution genomic techniques.
View Article and Find Full Text PDFAAPS PharmSciTech
September 2025
Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt.
The chimpanzee adenovirus-vectored vaccine developed by the University of Oxford (ChAdOx1 nCoV-19) showed good stability when stored in refrigerator. However, the vaccine manufacturer prefers its transportation in frozen condition. Data regarding the stability of the vaccine after exposure to repeated freezing processes have not been explored yet.
View Article and Find Full Text PDFEur Spine J
September 2025
Department of Spine Surgery, The People's Hospital of Guangxi Zhuang Autonomous Region, Guangxi, China.
Purpose: This study aims to assess the outcomes of combining oblique lumbar interbody fusion (OLIF) with anterolateral screw fixation (ASF) and stress endplate augmentation (SEA) in comparison to OLIF combined with pedicle screw fixation (PSF) for the treatment of degenerative lumbar spinal stenosis (DLSS) in patients with osteoporosis (OP).
Methods: We performed a retrospective analysis of patients diagnosed with DLSS who underwent OLIF in conjunction with either SEA and ASF (SEA-ASF group) or PSF (PSF group). Clinical outcomes, including the visual analog scale (VAS) scores for lumbar and leg pain, as well as the Oswestry Disability Index (ODI), were assessed at various postoperative intervals and compared to preoperative values.