98%
921
2 minutes
20
Background: Revision of a sleeve gastrectomy (SG) to a Roux-en-Y gastric bypass (RYGB) is indicated for gastroesophageal reflux disease (GERD) and for weight recurrence. Existing literature is conflicting and lacks long-term follow-up.
Objectives: To evaluate the resolution of GERD and additional weight loss after conversion of SG to RYGB.
Setting: Retrospective study of prospectively maintained multicentric bariatric surgery data sets.
Methods: Patients who underwent a conversion from SG to RYGB were divided in two groups based on the indication (GERD versus weight). Outcomes included total weight loss (TWL), GERD symptoms resolution, nutritional parameters, and postoperative complications such as reoperations and readmissions. The outcomes were compared between both groups.
Results: One hundred twenty-four patients with GERD versus 93 weight patients were included in the study. At the time of the revision, the weight group had a significantly higher body mass index (BMI) (42.3 ± 5.5 versus 34.7 ± 6.6kg/m, P < .0001). Both groups achieved comparable TWL following the revision (GERD:13 ± 8% versus weight 16 ± 7%, P = .529; 23/93 lost to follow-up in the weight group). At the 1-year follow-up, more than 75% of the patients had their GERD symptoms resolved (18/124 lost to follow-up). For postoperative outcomes, immediate postoperative complications were comparable between both groups (P = .754). Over an average follow-up period of 4 years following the revision, patients with GERD had more late reoperations (GERD: 14% versus weight: 4%, P = .016).
Conclusions: SG-to-RYGB conversion for GERD or weight recurrence helped achieve resolution of GERD symptoms as well as additional weight loss. GERD patients suffered from worse clinical outcomes following a revision RYGB in comparison to the weight recurrence patients.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.soard.2025.07.013 | DOI Listing |
Matern Child Health J
September 2025
University of Southern California, 1845 N Soto St, Los Angeles, CA, 90032, USA.
Objective: To test whether parent restriction, pressure to eat, and maternal concern for child weight mediated the positive association between food insecurity and child body mass index (BMI) in cross-sectional and longitudinal analysis.
Methods: Data were from mother-child pairs (n = 202 at baseline). Children were M = 10.
PLoS One
September 2025
The George Institute for Global Health, Imperial College London, London, United Kingdom.
Background: Tobacco use remains a major public health challenge in sub-Saharan Africa, with significant gendered dimensions. Place of residence is an important determinant, as rural and urban contexts shape exposure, access, and consumption patterns. This study investigates rural-urban disparities in tobacco use among women in sub-Saharan Africa, with a focus on quantifying the relative contributions of socioeconomic factors.
View Article and Find Full Text PDFAdv Ther
September 2025
Petauri Evidence, Nottingham, UK.
Introduction: Hemophilia A, an X-linked recessive bleeding disorder, is characterized by reduced factor VIII (FVIII) activity. Hemophilia A can significantly impact a person's quality of life because of the risk of spontaneous bleeding. Treatment for hemophilia A aims to prevent bleeding from occurring.
View Article and Find Full Text PDFKnee Surg Sports Traumatol Arthrosc
September 2025
Orthopaedic Research Foundation of Western Australia, Perth, Western Australia, Australia.
Purpose: The purpose of the study was to identify the safety and effectiveness of an accelerated (AR) versus conservative (CR) rehabilitation regimen following surgical repair of proximal hamstring tendon avulsions.
Methods: This prospective randomized controlled trial (RCT) allocated patients undergoing proximal hamstring tendon repair to either a braced, partial weight-bearing rehabilitation regime (CR = 30) or an accelerated, unbraced regime, which permitted full weight-bearing as tolerated (AR = 27). Patients were evaluated pre-operatively and at 6 weeks, 3 and 6 months post-surgery, via patient-reported outcome measures (PROMs), patient satisfaction and global rating of change (GRC) scores.
Adv Sci (Weinh)
September 2025
Department of Respiratory and Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China.
Obesity-associated obstructive sleep apnea (OSA) highlights the need for effective therapies. Hypothalamic endoplasmic reticulum (ER) stress contributes to leptin resistance in obesity. Although hesperidin (HE) modulates ER stress and oxidative pathways, its low bioavailability limits clinical use, its role in OSA is unknown.
View Article and Find Full Text PDF