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We discuss the complications associated with inferior vena cava (IVC) filters, focusing on a female patient in her mid-30s who presented to the emergency department with a history of hypercoagulable state and recurrent deep vein thrombosis. She had an IVC filter placed, followed by an IVC stent years later. The patient presented with severe lower back pain radiating to her right leg and back spasms. Investigations revealed an IVC filter tine extruding into the L3-L4 disc space, causing discitis-osteomyelitis, an intraosseous abscess and a psoas abscess. Another tine caused mild hydronephrosis by abutting the ureter. Methicillin-resistant was cultured from a disc aspirate. After initial antibiotic treatment, her spinal instability worsened, necessitating complex spinal surgery to remove three filter tines. This case highlights the significant risks of IVC filters, including fracture and organ perforation, and emphasises the critical importance of timely filter removal to prevent serious, though sometimes rare, outcomes.
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http://dx.doi.org/10.1136/bcr-2024-264581 | DOI Listing |
J Am Coll Cardiol
August 2025
Yale-New Haven Hospital/Yale Center for Outcomes Research and Evaluation, New Haven, Connecticut, USA; Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA; Department of Health Policy and Management, Yale School of Public Health,
JACC Adv
August 2025
CIBER de Enfermedades Respiratorias (CIBERES), Madrid, Spain; Chair for the Study of Thromboembolic Disease, Faculty of Health Sciences, UCAM-Universidad Católica San Antonio de Murcia, Guadalupe, Spain. Electronic address:
Background: Patients with cancer-associated venous thromboembolism (VTE) are at increased risk of both recurrent VTE and bleeding. These risks may vary by cancer site, but the magnitude of this variation remains unclear.
Objectives: The aim of the study was to compare 90-day risks of recurrent VTE or VTE-related death (composite outcome) and major bleeding across different cancer sites.
World J Clin Cases
September 2025
Department of Critical Care Medicine, The Second Affiliated Hospital of Zunyi Medical University, Zunyi 563000, Guizhou Province, China.
Background: Acute pulmonary thromboembolism is a complication of venous thrombosis. Extracorporeal membrane oxygenation (ECMO), an effective rescue measure for rapid hemodynamic recovery, can be used in patients for whom thrombolysis therapy has failed.
Case Summary: This case report describes an extreme rescue process for a patient with a preset inferior vena cava (IVC) filter in a relatively economically underdeveloped area with an insufficient supply of consumables.
Thromb Res
August 2025
Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States of America; Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States of America; Yale New Haven Hospital/Yale Center for Outcomes Res
Thromb Haemost
August 2025
Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States.
Lipoprotein(a) [Lp(a)] is a circulating plasma lipoprotein with structural similarities to low-density lipoprotein (LDL), distinguished by the addition of apolipoprotein(a) to the LDL structure. Lp(a) levels are approximately 80% genetically determined, and distinct components of this complex particle are thought to confer atherogenic, inflammatory, and antifibrinolytic properties contributing to cardiovascular risk. A growing body of evidence has shown a causal association between elevated Lp(a) levels and both atherosclerotic cardiovascular disease (ASCVD) and valvular aortic stenosis.
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