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Article Abstract

Alpha-particle emitters have garnered considerable interest as therapeutic radiopharmaceuticals, with At emerging as a viable candidate. In this study, the activity concentration of an At solution was determined via alpha-particle counting with a liquid scintillation spectrometer. Alpha-particles, in the region of interest set for pulse-height spectral measurement, were counted, and the counts were corrected for alpha-particle counting efficiency determined using Am standard source. The uncertainty in the alpha-particle counting efficiency was the largest contributor to the overall uncertainty. This result suggests that the combined uncertainty can be reduced by improving the method for evaluating alpha-particle counting efficiency.

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http://dx.doi.org/10.1016/j.apradiso.2025.112093DOI Listing

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