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Purpose Of Review: Evaluate literature examining whether mutual help groups (MHGs) for illicit drug use disorders benefit participants.
Recent Findings: Recent studies consistently show that MHG attendance and involvement predict reductions in drug use and addiction severity. More rigorous methodologies offer stronger evidence of effectiveness, but additional controlled trials are needed. Drug-focused MHG challenges include lower success rates of professionally-delivered interventions to facilitate participation compared to alcohol-focused MHGs, and stigma towards opioid agonist medications. Culturally-tailored MHG formats may benefit specific populations (e.g., racial/ethnic minorities). Non-12 step MHGs like SMART Recovery show promise, but research is limited. Online delivery formats positively affect retention.
Summary: Evidence on the benefits of MHGs for drug use disorders is encouraging but incomplete. MHG engagement may be enhanced by cultural adaptations and reduced stigma towards medications. Future research should focus on non-12 step MHGs, treatment integration, optimizing online formats, and understudied groups (e.g. Indigenous populations). Selection bias remains a challenge in evaluations of MHG effectiveness.
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http://dx.doi.org/10.1007/s40429-025-00635-w | DOI Listing |
Turk J Pediatr
September 2025
Department of Pathology, University of Health Sciences Antalya Education and Research Hospital, Antalya, Türkiye.
Background: Delirium in patients with ulcerative colitis may be seen, especially in the elderly and in patients hospitalized for a long time. In children, Wernicke's encephalopathy may occur due to thiamine deficiency in both ulcerative colitis and Crohn's disease. We present a patient with ulcerative colitis who presented with delirium as the first symptom, did not respond to steroid treatment and improved with anti-tumor necrosis factor-alpha treatment.
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September 2025
Department of Child and Adolescent Psychiatry, Ankara Bilkent City Hospital, Faculty of Medicine, Ankara Yıldırım Beyazıt University, Ankara, Türkiye.
Background: Intractable paroxysmal sneezing is a rare and diagnostically challenging condition in children, often mimicking organic diseases. While it is often addressed as psychogenic in the literature, our case presented findings suggestive of a tic disorder, highlighting the need for a broader diagnostic perspective.
Case Presentation: An 11-year-old girl was referred to the child and adolescent psychiatry clinic with a one-year history of persistent and fluctuating sneezing episodes.
Turk J Pediatr
September 2025
Division of Pediatric Hematology, Department of Pediatrics, Faculty of Medicine, Dokuz Eylül University, İzmir, Türkiye.
Background: Neutropenia is a common laboratory finding in children, therefore it is a common referral reason to pediatric hematology units. This study hypothesizes that most neutropenic children do not require pediatric hematology consultation, and that key clinical indicators can guide the need for referral.
Methods: Medical records of 180 patients who were admitted to a tertiary reference center, were evaluated in terms of demographical data, physical examination findings, laboratory findings, and outcome measures.
Purpose: In Armenia, a lower-middle-income country, cancer causes 21% of all deaths, with over half of cases diagnosed at advanced stages. Without universal health insurance, patients rely on out-of-pocket payments or black-market channels for costly immunotherapies, underscoring the need for real-world data to inform equitable policy reforms.
Methods: We conducted a multicenter, retrospective cohort study of patients who received at least one dose of an immune checkpoint inhibitor (ICI) between January 2017 and December 2023 across six Armenian oncology centers.
Neurology
October 2025
Neurology, Epilepsy and Movement Disorders Unit, Bambino Gesù Children's Hospital, IRCCS, Full Member of European Reference Network on Rare and Complex Epilepsies - EpiCARE, Rome, Italy.
Objectives: Neuronal ceroid lipofuscinosis type 3 (CLN3) is a rare lysosomal storage disorder characterized by progressive neurodegeneration. No disease-modifying treatments are currently available. Miglustat, a substrate reduction therapy, has shown preclinical efficacy in CLN3 models (conference abstract).
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