Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Identification and synthesis of highly conserved glycans is a priority for understanding chemical immunology as it applies to drug-resistant pathogens such as Gram-negative Acinetobacter baumannii. Herein, we report on our initial efforts aimed toward the synthesis of a highly conserved lipooligosaccharide core isolated originally from A. baumannii ATCC 19606. Key steps in the syntheses include a regioselective acetonide cleavage and a stereoselective and regioselective O-glycosylation of the 4-position of the 8-carbon sugar "Kdo."
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12416160 | PMC |
| http://dx.doi.org/10.1016/j.carres.2025.109639 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Synthesis of disaccharide and trisaccharide substructures of an A. baumannii lipooligosaccharide core.
Carbohydr Res
November 2025
Department of Chemistry, Louisiana State University, 232 Choppin Hall, Baton Rouge, LA, 70806, USA. Electronic address:
Identification and synthesis of highly conserved glycans is a priority for understanding chemical immunology as it applies to drug-resistant pathogens such as Gram-negative Acinetobacter baumannii. Herein, we report on our initial efforts aimed toward the synthesis of a highly conserved lipooligosaccharide core isolated originally from A. baumannii ATCC 19606.
View Article and Find Full Text PDFUnderstanding the population structure of using core genome multilocus sequence typing (cgMLST) and a life identification number (LIN) code classification system.
bioRxiv
May 2025
Nuffield Department of Population Health, University of Oxford.
is an important cause of infectious exacerbations of chronic obstructive pulmonary disease and otitis media. Previously, seroresistant (SR) and serosensitive (SS) lineages that differed in virulence potential were described, which raised questions about their evolutionary relationship and species classification. To investigate the population structure of , we developed a core-genome multilocus sequence typing (cgMLST) scheme using 1,319 core genes, and a life identification number (LIN) barcode classification system.
View Article and Find Full Text PDFouter membrane vesicles may transport biogenic elemental sulfur.
Appl Environ Microbiol
July 2025
Department of Biological Sciences, University of Delaware, Newark, Delaware, USA.
Outer membrane-derived vesicles (OMVs) have been studied in different phyla of gram-negative bacteria, most extensively in the Pseudomonadota, where they have been shown to participate in diverse biological and environmental processes. To date, the production of OMVs has not been reported in the Chlorobiaceae within the phylum Chlorobiota. is the model organism for the Chlorobiaceae that synthesizes and consumes insoluble extracellular sulfur (S(0)) globules by an unknown mechanism.
View Article and Find Full Text PDFMoraxella marmotae sp. nov. Isolated from the Respiratory Tract of Marmota himalayana.
Curr Microbiol
June 2025
Academy of Medical Sciences, Shanxi Medical University, Taiyuan, 030001, PR China.
Two novel Gram-stain-negative, Oxidase-positive, catalase-negative, aerobic, non-motile and coccus-shaped bacterial strains (ZJ142 and ZJ171) were isolated from the respiratory tract of marmots collected from Yushu Tibetan Autonomous Prefecture (Altitude: 3600 m; N: 33°13'57'', E: 97°1'11'') in Qinghai Province. The 16S rRNA genes of strains ZJ142 and ZJ171 are most similar to Moraxella porci DSM 25326 (99.04%).
View Article and Find Full Text PDFOuter Membrane Vesicles May Transport Biogenic Elemental Sulfur.
bioRxiv
May 2025
Department of Biological Sciences, University of Delaware, Newark, DE, 19716, USA.
Outer membrane-derived vesicles (OMVs) have been studied in different phyla of Gram-negative bacteria, most extensively in the Pseudomonadota, where they have been shown to participate in diverse biological and environmental processes. To date, the production of OMVs has not been reported in the Chlorobiaceae within the phylum Chlorobiota. is the model organism for the Chlorobiaceae that synthesizes and consumes insoluble extracellular sulfur (S(0)) globules by an unknown mechanism.
View Article and Find Full Text PDF