Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
, a destructive invasive species, threatens agriculture and ecosystems globally. Environmentally safe control methods like sex pheromones remain unexplored for this snail. Integrating behavioral tests, metabolomics, and field trials, we identified key chemical ecology traits. Male were strongly attracted to virgin female-conditioned water, specifically its medium ultrafiltrate, but unresponsive to male or mated female samples. Nontargeted metabolomics of 135 up-regulated metabolites in virgin females pinpointed 4-hydroxyphenylacetic acid as a critical attractant. Behavioral assays confirmed its unique efficacy in luring males, while structural analogs failed, indicating specificity. Field trials validated its practical trapping potential, with optimal performance at a concentration of 1 mol/L. This study identifies 4-hydroxyphenylacetic acid as a candidate component of sex pheromone in , offering a targeted strategy for eco-friendly population control. These findings advance invasive species management by enabling pheromone-based traps, reducing reliance on chemical pesticides and mitigating ecological impacts.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.jafc.5c06394 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Integrating Metabolomics and Behavioral Assays to Identify 4-Hydroxyphenylacetic Acid as a Candidate Component of Sex Pheromone in Invasive .
J Agric Food Chem
August 2025
Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection (Guangxi Normal University), Ministry of Education, Guilin, Guangxi 541006, China.
, a destructive invasive species, threatens agriculture and ecosystems globally. Environmentally safe control methods like sex pheromones remain unexplored for this snail. Integrating behavioral tests, metabolomics, and field trials, we identified key chemical ecology traits.
View Article and Find Full Text PDFSynthesis of Novel Bioactive Lipophilic Hydroxyalkyl Esters and Diesters Based on Hydroxyphenylacetic Acids.
Molecules
July 2025
Department of Agriculture and Forest Sciences (DAFNE), University of Tuscia, Via San Camillo de Lellis, 01100 Viterbo, Italy.
Novel lipophilic hydroxyalkyl esters were synthetized by Fischer esterification in good to excellent yields (60-96%) from a panel of hydroxyphenylacetic acids and increasing chain length (2 to 8 carbon atoms) α,ω-diols. The in vitro antioxidant activity of these compounds was evaluated by DPPH and ABTS assays. Hydroxybutyl esters and hydroxyphenylacetic acids were used as starting materials for the synthesis of novel lipophilic diesters (butyl diarylacetates) using Mitsunobu reaction.
View Article and Find Full Text PDFControl of and dual species interkingdom biofilm development via SAP5 inhibition.
Future Microbiol
August 2025
Department of Biotechnology, National Institute of Technology Raipur, Raipur, India.
Aim: Microbial biofilms, particularly polymicrobial ones formed by and , exhibit increased resistance to conventional treatment. This study investigates the inhibitory effect of 4-hydroxyphenylacetic acid on Secreted Aspartyl Protease 5, a key virulence factor involved in hyphal development and biofilm formation in , to investigate its therapeutic potential in inhibiting polymicrobial biofilms developed with .
Materials & Methods: Biofilm formation was studied using a Biofilm Infection Simulator System and polymethylmethacrylate coupons.
Effects of 4-hydroxyphenylacetic acid, a phenolic acid compound from Yucca schidigera extract, on immune function and intestinal health in meat pigeons.
Poult Sci
July 2025
Institute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Sciences, Beijing 100097, PR China. Electronic address:
This study aimed to evaluate the effects of 4-hydroxyphenylacetic acid (4-HPAA), a phenolic acid compound from Yucca schidigera extract, in Caco-2 cells and artificial rearing of pigeons. In vitro experiments showed that 4-HPAA at different levels exhibited higher cell viability than shikimic acid and 3,4-dihydroxybenzoic acid, and with the highest viability observed at 600 μM. Additionally, 600 μM 4-HPAA alleviated LPS-induced upregulation of IL-1β and CASPASE1 expressions (P < 0.
View Article and Find Full Text PDFGut microbiota-derived 4-hydroxyphenylacetic acid (4-HPAA) inhibits weight gain and is negatively associated with childhood obesity.
Transl Pediatr
June 2025
Department of Neonatology, Affiliated Children's Hospital of Jiangnan University, Wuxi Children's Hospital, Wuxi Key Laboratory of Genetic and Metabolic Diseases in Children, Wuxi, China.
Background: Childhood obesity has rapidly increased, becoming a significant global public health concern. Obese children exhibit distinct gut microbiome compositions compared to their normal-weight peers, leading to differences in the metabolic products derived from gut microbiota between the two groups. However, the causal relationship between these microbial-derived metabolites and childhood obesity remains unclear.
View Article and Find Full Text PDF