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Purpose: This study aims to examine how language background and grade level influence the voiceless sibilant fricative production of two groups of children enrolled in a Mandarin-English bilingual school in Canada. One group of children was exposed to Mandarin at home as heritage language (HL), and the other group had little to no exposure to Mandarin until they started learning it as a second language (L2) at school.
Method: Eighty-two children in Grades 1, 3, or 5 as well as 12 teachers engaged in picture-naming tasks in both English and Mandarin. Their speech production of voiceless sibilant fricatives was analyzed using both transcription and acoustic methods. The center of gravity (CoG) and F2 onset of the vowel following the fricatives were measured in the acoustic analysis.
Results: Both groups of children exhibited high accuracy rates in producing English /s/ and /ʃ/ and were able to distinguish the two English fricatives based on the CoG regardless of their grade level. For Mandarin fricatives, children in the higher grades achieved higher accuracy rates. Mandarin HL speakers had a higher accuracy rate than Mandarin L2 speakers, with their productions more closely resembling teachers' productions. The CoG distinguished all three Mandarin fricatives regardless of grade level and language background. However, significant differences in F2 onset were only observed in the HL group.
Conclusions: The finding that unshared fricatives were more difficult than shared ones, along with the significant impact of language background-but not grade level-on the accuracy of fricatives unique to Mandarin, suggests that students, even in higher grades, can benefit from more explicit teaching. The developmental patterns and error trends identified in this study can serve as a reference for speech assessment and aid in planning treatment or instructional sessions.
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http://dx.doi.org/10.1044/2025_JSLHR-25-00061 | DOI Listing |
Int J Gen Med
September 2025
Department of Dermatology, Hangzhou Third People's Hospital, Hangzhou Third Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, People's Republic of China.
Background: Nodular hidradenoma (NH) is a rare benign adnexal tumor originating from sweat glands, often misdiagnosed due to nonspecific clinical manifestations. Ultrasonography (US) plays a critical role in the diagnosis of skin tumors, yet systematic descriptions of its sonographic features remain limited.
Objective: This study aims to investigate the very-high-frequency (VHF) characteristics of eccrine nodular hidradenoma (ENH) and establish key imaging criteria to differentiate it from other cutaneous/subcutaneous lesions.
J Exp Pharmacol
September 2025
Department of Translational Medicine, University of Ferrara, Ferrara, Italy.
Purpose: Acute graft-versus-host disease (aGVHD) is a significant cause of death in recipients of allogeneic hematopoietic stem cell transplantation. In this type of graft, the intestine is particularly affected, with the loss of intestinal barrier integrity playing a key role in its onset. In this scenario, the aim of the present research was to evaluate defibrotide, a heparin-like compound, marked for severe veno-occlusive disease, as an innovative therapeutic approach for restoring intestinal barrier integrity using an in vitro model and analyzing aGVHD patients' sera and clinical data.
View Article and Find Full Text PDFBiochem Biophys Rep
June 2025
The Affiliated Traditional Chinese Medicine Hospital, Guangzhou Medical University, Guangzhou, Guangdong Province, China.
Background: SLC16A3, a highly expressed H + -coupled symporter, facilitates lactate transport via monocarboxylate transporters (MCTs), contributing to acidosis. Although SLC16A3 has been implicated in tumor development, its role in tumor immunity remains unclear.
Methods: A pan-cancer analysis was conducted using datasets from The Cancer Genome Atlas, Cancer Cell Line Encyclopedia, and Genotype-Tissue Expression projects.
Front Psychiatry
August 2025
College of Educational Science, Jiangsu Second Normal University, Nanjing, China.
Background: Research has revealed that presence of meaning in life may be a protective factor for life satisfaction among young adults in China. However, few studies have examined the underlying mechanisms that may mediate or moderate this association. This study aimed to test the mechanisms underlying the relationship between meaning in life and life satisfaction among young adults in China.
View Article and Find Full Text PDFAlpha Psychiatry
August 2025
Center for Studies of Psychological Application, Guangdong Key Laboratory of Mental Health and Cognitive Science, and School of Psychology, South China Normal University, 510631 Guangzhou, Guangdong, China.
Background: Children's mental health is significantly influenced by family environments, where multiple risks often coexist, exert unequal impacts, and combine in different configurations that can result in diverse developmental outcomes. This study examines how different configurations of cumulative family risks influence mental health symptoms in Chinese children using a novel person-centered approach.
Materials And Methods: Data were collected through a large-scale, semester-based comprehensive survey of 34,041 children in Grades 4 to 6 in an economically underdeveloped county-level city in Guangdong, China, during November and December, 2022.