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We describe a 65-year-old male ophthalmologist who experienced a brief episode of transient monocular vision loss in his left eye, characterized as a "gray-out" lasting a few seconds. Utilizing his medical expertise, the patient recorded the blood flow in his ophthalmic artery, capturing a rare real-time visualization of embolus migration from the central to peripheral regions. The embolism resolved spontaneously, restoring normal vision. Duplex ultrasound revealed high-grade stenosis in the proximal left internal carotid artery, with a peak systolic velocity of 421 cm/s and an end-diastolic velocity of 188 cm/s, consistent with over 90% stenosis. A computed tomography angiogram confirmed the presence of an ulcerated plaque, attributing the vision loss to emboli originating from the carotid artery. Because of the critical stenosis and risk of further cerebrovascular events, a semiurgent left carotid endarterectomy was performed under regional anesthesia. The procedure was completed without complications, and the patient's vision remained normal postoperatively. This case highlights the unique real-time documentation of an embolic event in an ophthalmologist who recognized the pathophysiology, emphasizing the importance of timely diagnosis and intervention, particularly carotid endarterectomy, in preventing stroke and irreversible vision loss in patients with high-grade internal carotid artery stenosis.
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http://dx.doi.org/10.1016/j.jvscit.2025.101915 | DOI Listing |
Clin Exp Optom
September 2025
School of Optometry and Vision Science, University of New South Wales, Sydney, Australia.
Clinical Relevance: Good vision is critical for childhood development and education. Pre-school vision screening is important for early detection and treatment of visual problems, and prevention of life-long vision loss.
Background: The aim of this study was to determine the prevalence of vision impairment (VI) and refractive error (RE) in rural Nepalese children under five years of age.
J Cataract Refract Surg
July 2025
Department of Ophthalmology, Santo António Local Health Unit, Porto, Portugal.
Purpose: To demonstrate the efficacy and safety of iris-claw phakic intraocular lens (pIOL) in the treatment of post keratoplasty astigmatism.
Setting: Cornea Unit, Ophthalmology Department - Unidade Local de Saúde de Santo António - Porto, Portugal.
Design: Retrospective longitudinal study.
Pract Neurol
September 2025
Neurology Department, Croydon University Hospital, London, England, UK
A 22-year-old woman had an 8-year history of progressive bilateral vision loss and of diabetes mellitus. Her mother had diabetes and two first cousins had severe congenital deafness. On examination, her visual acuities were 6/36 bilaterally, with absent colour vision and gross optic disc pallor.
View Article and Find Full Text PDFInj Prev
September 2025
Biomedical Research Foundation, Dhaka, Bangladesh
Background: During the student-led mass uprising in Bangladesh in July 2024, over 1300 cases of eye injuries were reported, with several hundred resulting in permanent blindness. However, the broader aftermath-encompassing financial hardship, social exclusion and psychological trauma-remains largely unexplored.
Objective: To assess the psychological, social and financial consequences of ocular injuries among survivors of the July 2024 protests in Bangladesh.
Cell Signal
September 2025
Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Hefei 230022, Anhui, China; NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract (Anhui Medical University), No. 81 Meishan Road, Hefei 230032, Anhui, China; Engin
Leber's hereditary optic neuropathy (LHON), a mitochondrial disorder marked by central vision loss, exhibits incomplete penetrance and male predominance. Since there are no adequate models for understanding the rapid vision loss associated with LHON, we generated induced pluripotent stem cells (iPSCs) from LHON patients carrying the pathogenic m.3635G > A mutation and differentiated them into retinal pigment epithelium (RPE) cells.
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