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Patients with autoimmune rheumatologic diseases (ARDs) exhibit an elevated risk for atherosclerosis, not fully accounted for by traditional risk factors alone. This review aims to explore how advanced multimodality cardiovascular imaging techniques can provide critical insights into the shared inflammatory pathways that contribute to endothelial damage and the development of atherosclerotic coronary artery disease. By highlighting the diagnostic potential and future applications of these techniques, we aim to provide a comprehensive overview for clinicians and researchers.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352401 | PMC |
http://dx.doi.org/10.14797/mdcvj.1646 | DOI Listing |
Eur Heart J Cardiovasc Imaging
September 2025
Department of Diagnostic and Interventional Radiology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Aims: Fetal circulation undergoes complex changes in congenital heart disease (CHD) that are challenging to assess with fetal echocardiography. This study aimed to assess clinical feasibility and diagnostic value of 4D flow cardiac magnetic resonance (CMR) in fetal CHD.
Methods And Results: Pregnant women in advanced third trimester pregnancy with fetal CHD were prospectively recruited for fetal CMR between 08/2021 and 11/2024.
Eur J Endocrinol
September 2025
Division of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic, Rochester, Minnesota, 55905.
Objective: Identify social/metabolic risk factors associated with subsequent diagnosis of adrenal adenoma.
Design: Population-based historical case-control study.
Methods: Cases were adult patients diagnosed with an adrenal adenoma between 2005-2017 with no overt hormone excess.
Arterial thrombosis is a multifaceted process characterized by platelet aggregation and fibrin deposition, leading to the occlusion of blood vessels. It plays a central role in cardiovascular conditions such as myocardial infarction and ischemic stroke. Gaining insight into the mechanisms underlying arterial thrombosis is essential for developing effective treatments aimed at preventing thrombotic events and reducing associated health burdens.
View Article and Find Full Text PDFCell Rep
September 2025
International Joint Laboratory for Drug Target of Critical Illnesses, School of Pharmacy, Nanjing Medical University, Nanjing 211166, China; Department of Nephrology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Electronic address:
Neurons that encode odor information are fundamental to innate fear processes, yet how mitral/tufted (M/T) cells encode innate fear remains unknown. Here, we identify three different response patterns of M/T cells in the dorsal olfactory bulb (dOB) during active avoidance elicited by non-dehydrogenated 2,4,5-trimethylthiazole (nTMT) through in vivo calcium imaging and multielectrode recordings in mice, including enhanced responses, suppressed responses, and no response. Remarkably, suppressed response M/T cells encode active avoidance, whereas suppressed and enhanced response M/T cells jointly encode passive freezing.
View Article and Find Full Text PDFJ Clin Invest
September 2025
Metabolism Unit, Massachusetts General Hospital and Harvard Medical School, Boston, United States of America.
Background: Statin therapy lowers the risk of major adverse cardiovascular events (MACE) among people with HIV (PWH). Residual risk pathways contributing to excess MACE beyond low-density lipoprotein cholesterol (LDL-C) are not well understood. Our objective was to evaluate the association of statin responsive and other inflammatory and metabolic pathways to MACE in the Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE).
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