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Backgrounds: Both isometric resistance training (ISO-RT) and dynamic resistance training (DYN-RT) are commonly used interventions to improve muscular strength. Unlike DYN-RT, which involves producing force through a joint range of motion, ISO-RT generates force without joint movement. However, their relative effectiveness for improving strength remains unclear, making it essential to clarify these differences to better guide exercise prescription across diverse populations and training goals.
Objectives: This systematic review and a meta-analysis investigated the effects of ISO-RT versus a non-exercise control (CTRL) or DYN-RT on isometric and isokinetic muscular strength in healthy adults.
Methods: Four databases (PubMed/MEDLINE, SPORTDiscus, Embase, and Scopus) were searched up to May 2025. Randomised and non-randomised controlled trials, including adults (18-45 years), were eligible for inclusion. Random-effects meta-analyses were conducted, with outcomes reported as standardised mean differences (SMD) and 95 % confidence intervals (CIs).
Results: A total of 32 studies involving 621 participants were included. ISO-RT significantly improved combined isometric and isokinetic strength compared to CTRL (SMD = 0.65; 95 % CI: 0.52-0.77; p < 0.0001) and DYN-RT (SMD = 0.35; 95 % CI: 0.21-0.48; p < 0.0001). Subgroup analyses revealed greater isometric strength gains with ISO-RT compared to DYN-RT (SMD = 0.43; p < 0.0001), whilst no statistically significant difference was observed for isokinetic strength between these RT modalities (SMD = -0.20; p = 0.24).
Conclusions: Overall, our findings indicate that ISO-RT resulted in greater isometric strength gains compared to DYN-RT and CTRL, whilst isokinetic strength gains were similar between these RT modalities. These findings indicate that ISO-RT may be an effective modality for enhancing muscular strength and could be considered a viable alternative or complement to DYN-RT.
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http://dx.doi.org/10.1016/j.jsams.2025.07.011 | DOI Listing |
Prim Care Diabetes
September 2025
Department of Health Sciences and Human Performance Department, College of Natural and Health Sciences, The University of Tampa, Tamp, FL, USA. Electronic address:
Aim: This study aims to compare the weekly resistance training (RT) frequency between people with diabetes, prediabetes, and without diabetes.
Methods: A total of 536,703 participants from 2017 to 2023 Behavioral Risk Factors Surveillance System were included in the analysis. Unadjusted and adjusted Poisson regression was performed to compare weekly resistance training frequency among participants with different diabetes statuses (without diabetes, prediabetes, and with diabetes).
BMJ Open
September 2025
Department of Rehabilitation, Shengjing Hospital of China Medical University, Shenyang, Liaoning, Chinax
Objectives: This study evaluated the effects of proximal core training on biomechanical risk factors and strength parameters in individuals at high risk of anterior cruciate ligament (ACL) injury (specifically: those exhibiting pathological movement patterns, neuromuscular deficits or biomechanical risk factors) and compared direct versus indirect interventions. We hypothesised that targeted training enhances dynamic knee stabilisation and hip control during high-risk manoeuvres, with direct approaches providing superior biomechanical benefits through neuromuscular control optimisation.
Design: Systematic review and meta-analysis using the Grading of Recommendation, Assessment, Development and Evaluation (GRADE) approach.
Hum Reprod
September 2025
Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA.
Study Question: Does weight loss from a hypocaloric dietary intervention improve antral follicle dynamics in women with PCOS?
Summary Answer: During a 3-month hypocaloric dietary intervention, women with PCOS who experienced clinically meaningful weight loss showed more organized antral follicle development including fewer recruitment events, but no change in the overall frequency of selection, dominance, or ovulation.
What Is Known Already: There is a spectrum of disordered antral follicle development in women with PCOS including excessive follicle recruitment and turnover, decreased frequency of selection and dominance, and failure of ovulation. Lifestyle intervention aimed at weight loss is recommended to improve metabolic health in women with PCOS yet benefits on ovarian follicle development and ovulation are unclear.
JAMA Psychiatry
September 2025
School of Psychological Sciences, Monash University, Melbourne, Victoria, Australia.
Importance: Cannabis is the most commonly used illicit drug, with 10% to 30% of regular users developing cannabis use disorder (CUD), a condition linked to altered hippocampal integrity. Evidence suggests high-intensity interval training (HIIT) enhances hippocampal structure and function, with this form of physical exercise potentially mitigating CUD-related cognitive and mental health impairments.
Objective: To determine the impact of a 12-week HIIT intervention on hippocampal integrity (ie, structure, connectivity, biochemistry) compared with 12 weeks of strength and resistance (SR) training in CUD.
Curr Sports Med Rep
September 2025
Family Medicine, Uniformed Services University, Family and Sports Medicine, Travis AFB, CA.
Bone stress injury is a common musculoskeletal condition presenting with insidious bony pain that is progressive and occurs with a number of intrinsic or extrinsic risk factors, particularly with a recent change in training. When elicited, the presence of bony tenderness remains the most important component of the physical exam, although reproduction at deeper sites is a challenge and requires a high index of suspicion and imaging for diagnosis. MRI should be utilized as the gold standard for diagnosis, grading, and return-to-sport timing prognosis when available, with plain radiographs used as first-line imaging.
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