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The improved stability and controllability of robotics has the potential to expand the spectrum of reconstructive surgery. Until recently, however, no robot was designed specifically for microsurgery. The present study aims to summarize the clinical pearls and pitfalls of utilizing the Symani Surgical System in microsurgical practice.The PubMed Database was queried using the search term "Symani Robot System" from inception until January 2025. Data regarding demographics, study design, technique, and surgical outcomes were extracted from the full text by two independent reviewers.In the present analysis, 21 publications encompassing the results of 397 patients (range: 1-100) and 642 robotic anastomoses were included. Of the 335 patients included in the studies that reported complication rates, pooled analysis yielded an overall complication rate of 14.03% ( = 47) and a partial or complete flap loss rate of 2.09% ( = 7). Of 642 robotic total anastomoses, only 1.24% ( = 8) required a transition to a manual approach. A total of 19 groups (90.47%) reported high precision of Symani, 15 (71.43%) highlighted improved surgical access to deeper anatomical fields, and 12 (57.15%) reported enhanced microsurgical ergonomics. Regarding limitations, 13 (61.90%) cited the expense of the system, 5 (23.81%) reported a lack of haptic feedback, 5 (23.81%) identified instrument "stickiness" as a factor slowing operations, and 3 (14.29%) highlighted the need for improved grip. The learning curve associated with Symani was discussed in 15 studies (71.43%).The results of the present literature review demonstrate that the Symani robot offers numerous benefits that will help advance the field of microsurgery. It provides complete tremor elimination, motion scaling, and improved operative ergonomics, leading to patent anastomosis and complication rates comparable to a traditional manual approach. However, more data are needed before widespread clinical implementation to determine whether the increased precision and controllability outweigh the cost and learning curve.The present study highlights the use of the Symani Surgical System, a novel robotic system designed specifically for microsurgery. Symani offers increased precision, dexterity, controllability, and numerous benefits that will help advance the field.
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http://dx.doi.org/10.1055/a-2659-7126 | DOI Listing |
J Ultrasound Med
September 2025
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Tremendous advances in ultrasound equipment and knowledge have expanded possibilities for the first trimester detailed ultrasound examination. Recommendations from national organizations to offer this service to patients with indications, coupled with recent modifications for dual use of the current procedural terminology code 76811 during pregnancy, will result in increased demand from patients and referring physicians. While proper reimbursement may motivate healthcare professionals to incorporate the first trimester detailed ultrasound examination into their practice and raise the standards of care in the first trimester, it can also be a challenging transition.
View Article and Find Full Text PDFJ Int Med Res
September 2025
Department of Orthopedics and Traumatology, Health Sciences University Fatih Sultan Mehmet Training and Research Hospital, Turkey.
ObjectiveTo determine the effectiveness of bilateral decompression combined with a unilateral transforaminal lumbar interbody fusion approach in centralizing a lordotic cage and preventing contralateral radiculopathy by ensuring equal foraminal elevation.MethodsThis is a retrospective cohort study based on clinical records and radiological data. Eighty-seven patients diagnosed with lumbar spinal stenosis at L3-S1 levels underwent bilateral decompression and transforaminal lumbar interbody fusion between 2017 and 2022.
View Article and Find Full Text PDFCureus
September 2025
Department of Urology, Gunma University School of Medicine, Maebashi, JPN.
Syphilis cases are increasing in Japan, highlighting the urgent need for rapid and accurate diagnosis. In primary syphilis, serological tests may yield negative results, so direct microscopic observation of remains an important but often underused diagnostic method. We present a simple, widely accessible phase-contrast microscopy system, featuring a USB camera and monitor, enabling high-clarity, real-time observation of live wild-type treponemes directly from patient lesions.
View Article and Find Full Text PDFJ Affect Disord
September 2025
King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Psychological Medicine, London, SE5 9RT, UK; National Institute for Health and Care Research (NIHR) Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College Lond
Although inflammation has been suggested as a promising therapeutic target for major depressive disorder (MDD), uncertainty remains about how to recognise individuals who may benefit from anti-inflammatory treatments. Transcriptomic profiles provide an important tool to identify relevant biological mechanisms associated with response. In this study, we investigate: i) the ability of transcriptomic profiles to predict antidepressant response to anti-inflammatory treatment with minocycline, and ii) the effect of minocycline on transcriptomic profiles based on the antidepressant response.
View Article and Find Full Text PDFJ Infus Nurs
August 2025
Author Affiliations: PGY-1 Pharmacy Practice Resident (Dr Van), Infectious Diseases Clinical Pharmacy Specialist (Dr Lee), University of California, Irvine Medical Center; and School of Pharmacy and Pharmaceutical Sciences (Dr Johannesmeyer), University of California, Irvine.