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With the explosive growth of Internet of Things (IoT) devices, massive amounts of heterogeneous data are continuously generated. However, IoT data transactions and sharing face multiple challenges such as limited device resources, untrustworthy network environment, highly sensitive user privacy, and serious data silos. How to achieve fine-grained access control and privacy protection for massive devices while ensuring secure and reliable data circulation has become a key issue that needs to be urgently addressed in the current IoT field. To address the above challenges, this paper proposes a blockchain-based data transaction and privacy protection framework. First, the framework builds a multi-layer security architecture that integrates blockchain and IPFS and adapts to the "end-edge-cloud" collaborative characteristics of IoT. Secondly, a data sharing mechanism that takes into account both access control and interest balance is designed. On the one hand, the mechanism uses attribute-based encryption (ABE) technology to achieve dynamic and fine-grained access control for massive heterogeneous IoT devices; on the other hand, it introduces a game theory-driven dynamic pricing model to effectively balance the interests of both data supply and demand. Finally, in response to the needs of confidential analysis of IoT data, a secure computing scheme based on CKKS fully homomorphic encryption is proposed, which supports efficient statistical analysis of encrypted sensor data without leaking privacy. Security analysis and experimental results show that this scheme is secure under standard cryptographic assumptions and can effectively resist common attacks in the IoT environment. Prototype system testing verifies the functional completeness and performance feasibility of the scheme, providing a complete and effective technical solution to address the challenges of data integrity, verifiable transactions, and fine-grained access control, while mitigating the reliance on a trusted central authority in IoT data sharing.
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http://dx.doi.org/10.3390/s25154854 | DOI Listing |
Clin Appl Thromb Hemost
September 2025
Pediatric Hematology Laboratory, Division of Hematology/Oncology, Department of Pediatrics, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, Guangdong, China.
Hemophilia, an X-linked monogenic disorder, arises from mutations in the or genes, which encode clotting factor VIII (FVIII) or clotting factor IX (FIX), respectively. As a prominent hereditary coagulation disorder, hemophilia is clinically manifested by spontaneous hemorrhagic episodes. Severe cases may progress to complications such as stroke and arthropathy, significantly compromising patients' quality of life.
View Article and Find Full Text PDFJ Synchrotron Radiat
November 2025
State Key Laboratory of Chemical Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, People's Republic of China.
This study develops an integrated X-ray absorption spectroscopy (XAS) photoemission electron microscopy (PEEM) platform on beamline BL09U at the Shanghai Synchrotron Radiation Facility (SSRF), enabling nanoscale characterization of complex materials through energy-resolved imaging and local-area XAS. By using the wide range of energy tunability, full access to different polarizations and PEEM's surface sensitivity, we have established a gap-monochromator control system under the EPICS framework to synchronize the elliptically polarized undulator (EPU) gap and monochromator energy dynamically, optimizing photon flux stability for absorption fine structure analysis. Combining X-ray magnetic circular dichroism (XMCD) and X-ray magnetic linear dichroism (XMLD) with PEEM and local-area XAS, this platform achieves concurrent mapping of electronic structures and magnetic domains in ferromagnetic nano-patterns, as demonstrated through our studies of NiFe Permalloy using this system.
View Article and Find Full Text PDFQual Life Res
September 2025
Department of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, 250012, Shandong, China.
Purpose: The study aimed to assess the interconnection of quality of life (QoL) variables and identify key areas for which interventions could improve QoL among men who have sex with men (MSM) living with HIV on antiretroviral therapy (ART).
Methods: A cross-sectional study was conducted in Jinan of Shandong Province, between October to December 2020. Undirected network analyses were conducted to examine and visualize the interconnections between QoL variables among MSM living with HIV.
Cancer Causes Control
September 2025
Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA.
Purpose: The U.S. Preventive Services Task Force recommends that men aged 55-69 years undergo shared decision-making (SDM) regarding prostate cancer (PCa) screening, and routine screening is not recommended for older men or those with limited life expectancy.
View Article and Find Full Text PDFManaging diabetes in older adults requires balancing long-term glycaemic control with the prevention of hypoglycaemia, to which this population is particularly vulnerable owing to frailty, multimorbidity and cognitive decline. Guidelines recommend individualized glucose targets for older adults, particularly those with multimorbidity or increased hypoglycaemia risk. For individuals with frailty or cognitive impairment, relaxed HbA1c targets are often appropriate to reduce the risk of adverse events.
View Article and Find Full Text PDF