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The accurate detection of small objects remains a critical challenge in autonomous driving systems, where improving detection performance typically comes at the cost of increased model complexity, conflicting with the lightweight requirements of edge deployment. To address this dilemma, this paper proposes LEAD-YOLO (Lightweight Efficient Autonomous Driving YOLO), an enhanced network architecture based on YOLOv11n that achieves superior small object detection while maintaining computational efficiency. The proposed framework incorporates three innovative components: First, the Backbone integrates a lightweight Convolutional Gated Transformer (CGF) module, which employs normalized gating mechanisms with residual connections, and a Dilated Feature Fusion (DFF) structure that enables progressive multi-scale context modeling through dilated convolutions. These components synergistically enhance small object perception and environmental context understanding without compromising network efficiency. Second, the neck features a hierarchical feature fusion module (HFFM) that establishes guided feature aggregation paths through hierarchical structuring, facilitating collaborative modeling between local structural information and global semantics for robust multi-scale object detection in complex traffic scenarios. Third, the head implements a shared feature detection head (SFDH) structure, incorporating shared convolution modules for efficient cross-scale feature sharing and detail enhancement branches for improved texture and edge modeling. Extensive experiments validate the effectiveness of LEAD-YOLO: on the nuImages dataset, the method achieves 3.8% and 5.4% improvements in mAP@0.5 and mAP@[0.5:0.95], respectively, while reducing parameters by 24.1%. On the VisDrone2019 dataset, performance gains reach 7.9% and 6.4% for corresponding metrics. These findings demonstrate that LEAD-YOLO achieves an excellent balance between detection accuracy and model efficiency, thereby showcasing substantial potential for applications in autonomous driving.
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http://dx.doi.org/10.3390/s25154800 | DOI Listing |
Neural Netw
September 2025
School of Electronic Science and Engineering, Nanjing University, China. Electronic address:
The Segment Anything Model (SAM) is a cornerstone of image segmentation, demonstrating exceptional performance across various applications, particularly in autonomous driving and medical imaging, where precise segmentation is crucial. However, SAM is vulnerable to adversarial attacks that can significantly impair its functionality through minor input perturbations. Traditional techniques, such as FGSM and PGD, are often ineffective in segmentation tasks due to their reliance on global perturbations that overlook spatial nuances.
View Article and Find Full Text PDFAdv Sci (Weinh)
September 2025
Department of Occupational Health (Key Laboratory of Electromagnetic Radiation Protection, Ministry of Education), Army Medical University (Third Military Medical University), Chongqing, 400038, China.
Cadmium (Cd) is a heavy metal that exhibits strong carcinogenic properties and promotes breast cancer (BC) progression. Autophagic flux dysfunction is involved in Cd-induced BC progression, but the underlying molecular mechanisms remain unclear. Here, it is observed that impaired autophagic flux and metabolic reprogramming are notable features related to Cd-induced proliferation, migration, and invasion in BC cell lines, including T-47D and MCF-7 cells.
View Article and Find Full Text PDFSmall Sci
September 2025
Infrared photodetectors are crucial for autonomous driving, providing reliable object detection under challenging lighting conditions. However, conventional silicon-based devices are limited in their responsivity beyond 1100 nm. Here, a scallop-structured silicon photodetector integrated with tin-substituted perovskite quantum dots (PQDs) that effectively extends infrared detection is demonstrated.
View Article and Find Full Text PDFFront Biosci (Landmark Ed)
August 2025
Department of Hepatobiliary Surgery, General Hospital of Ningxia Medical University, 750004 Yinchuan, Ningxia Hui Autonomous Region, China.
Background: Mediator complex subunit 10 (MED10) serves as a critical regulator of eukaryotic gene expression by facilitating RNA polymerase II activity. Our investigation aims to characterize MED10's functional contributions and underlying molecular pathways in hepatocellular carcinoma (HCC) development.
Methods: MED10 expression patterns in HCC and their correlation with clinicopathological parameters and patient outcomes were examined using bioinformatics databases and immunohistochemistry.
CRISPR homing gene drive is a disruptive biotechnology developed over the past decade with potential applications in public health, agriculture, and conservation biology. This technology relies on an autonomous selfish genetic element able to spread in natural populations through the release of gene drive individuals. However, it has not yet been deployed in the wild.
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