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Background: Global uptake of the Baby Friendly Hospital Initiative (BFHI) and Ten Steps to Successful Breastfeeding (Ten Steps) is low, and sustainability is a challenge. Although both programs are backed by strong evidence and international endorsement, their integration into national health systems has been inconsistent and often lacks institutional prioritization. This study aimed to analyze challenges to implementation of the BFHI and Ten Steps programs in Australia and Indonesia.
Methods: We used the Non-adoption, Scale-up, Spread and Sustainability (NASSS) framework and categorized the relative complexity of implementing the program into each setting.
Results: Most BFHI/Ten Steps implementation domains were categorized as complicated or complex, and the policy level, organizational and community settings for the intervention overlapped for most domains. Despite the cultural and health systems differences between Australia and Indonesia, both environments present challenges and also unique opportunities for the uptake and scale up of BFHI/Ten Steps with the right support and adaptation. Importantly, the complexity was not only technical but also institutional, with implementation often relying on individual champions rather than systemic support.
Conclusions: Systems that require and motivate compliance to the WHO Code (Step 1) and optimize healthcare professionals' (HCP) lactation support capacity (Step 2) are crucial, and need to be regulated and coordinated from the national level. To achieve optimal support for initiating and establishing breastfeeding, governments, facilities, and relevant HCPs must support birth models that ensure women receive continuity of care and adequate time with skilled midwives, who in turn are educated in ways that are free from commercial influence (Step 1). These policy and clinical level steps can reduce the misalignment of costs and benefits of BFHI and Ten Steps implementation. Strengthening institutional commitment and embedding BFHI into national quality frameworks may further enhance sustainability and scale-up. A coordinated, system-wide approach is essential to ensure these evidence-based practices become standard in maternal and newborn care.
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http://dx.doi.org/10.1186/s13006-025-00754-0 | DOI Listing |
Anal Chim Acta
November 2025
Chemical and Veterinary Investigations Office Stuttgart, Schaflandstraße 3/2, 70736, Fellbach, Germany.
Background: Previous studies involving cleanup via conventional solid-phase extraction (SPE) materials to overcome matrix effects for the polar organophosphonate and -phosphinate pesticides glyphosate, glufosinate, ethephon, fosetyl, and their various metabolites often showed limitations due to the existence of various matrix compounds in plant commodities with similar polarity. To overcome existing drawbacks, we utilized the unique selectivity provided by metal oxides as SPE materials. These were exploited in a novel automated online SPE-LC-MS/MS method which allowed analyte-specific trapping in the presence of excessive amounts of matrix compounds as typically contained in extracts of the Quick Polar Pesticides (QuPPe) method.
View Article and Find Full Text PDFMidwifery
August 2025
Department of Nursing, School of Health Sciences, Cyprus University of Technology, Limassol, Cyprus.
Background: The effect of Breastfeeding Self-efficacy (BFSE) and the Baby-Friendly Hospital Initiative's (BFHI) 10 Steps on breastfeeding initiation, continuation and exclusivity, is well established. However, direct evidence about the association between the experience of the 10 steps and self-efficacy is limited.
Objective: To assess the association between adherence to the 'Ten Steps to Successful Breastfeeding', sociodemographic factors and other predictors with breastfeeding self-efficacy (BFSE) at 48 h and at one month postpartum.
Front Immunol
September 2025
Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Ten Eleven Translocation (TET) proteins can oxidize 5-methylcytosine to generate in sequential steps oxidized forms of cytosine: 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine. Through their catalytic activity TET proteins promote active DNA demethylation. There are three TET proteins: TET1, TET2 and TET3.
View Article and Find Full Text PDFGynecol Oncol
September 2025
Department of Gynecologic Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China. Electronic address:
Objective: To evaluate the feasibility, safety, and quality of a standardized technique for single-port laparoscopic paraaortic lymphadenectomy guided by a novel anatomical concept.
Methods: This single-center prospective study enrolled patients with gynecological cancers requiring paraaortic lymphadenectomy from February 2022 to May 2025. All patients underwent single-port laparoscopic paraaortic lymphadenectomy using a standardized technique grounded in a novel "renal vein angle" anatomical concept.
J Chromatogr B Analyt Technol Biomed Life Sci
August 2025
Academy of Forensic Science, Shanghai Key Laboratory of Forensic Medicine Shanghai Forensic Service Platform, Key Laboratory of Forensic Science, Ministry of Justice, Shanghai 200063, China.
Benzodiazepines and Z-drugs are commonly used as prescription medications to treat anxiety, epilepsy, insomnia, and alcohol withdrawal syndrome, but their use can lead to tolerance, dependence, and withdrawal reactions if taken against official guidelines. Furthermore, designer benzodiazepines, most of which lack clinical and toxicological data, have entered the illicit drug market as new psychoactive substances and are used for recreational purposes. Their abuse can cause confusion, memory loss, respiratory depression, and even death, especially when combined with other sedative-hypnotics or alcohol.
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