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Background: The use of long-term devices for chemotherapy in neoplastic diseases is very common. The CAVA trial was an extensive study that prospectively evaluated more than 1000 patients undergoing chemotherapy and randomly allocated them to three groups based on the type of catheters used: peripherally inserted central catheters, Port, or Hickmann. For this study, the Quality of Life Vascular Access Device (QoLVAD) questionnaire was administered to assess the impact of these devices (abovementioned catheters) on the patients' daily lives. routine However, no Brazilian Portuguese version of the questionnaire exists, hindering its use among Brazilian patients.
Objective: To translate the CAVA trial QoLVAD to Brazilian Portuguese and validate it so that it can be used in the Brazilian population.
Methods: A total of 167 patients with long term vascular access devices for chemotherapy participated in the study. After translation and retranslation, construct validity was analyzed by identifying the correlation between QoLVAD and the European Quality of Life Questionnaire (EuroQol). To determine the reliability, internal consistency and test-retest analysis with at least a 7-day interval between two administrations of the questionnaire were calculated.
Results: The results revealed good internal and external consistency of the QoLVAD. Significant correlations were found between the QoLVAD and EuroQol (r -0,658 and p<0.001).
Conclusion: The Brazilian Portuguese version of the QoLVAD exhibited good clinimetric properties and proved to be applicable to the Brazilian population.
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http://dx.doi.org/10.31744/einstein_journal/2025AO1665 | DOI Listing |
Climacteric
September 2025
Gynecology Discipline, Obstetrics and Gynecology Department, University of São Paulo School of Medicine, São Paulo, Brazil.
Objective: Social media is an increasingly relevant tool for health education, enabling information exchange, promoting autonomy and supporting informed decision-making. This study introduces Menopausando, a predominantly Portuguese-language digital platform designed to support women during menopausal transition and postmenopause.
Method: This cross-sectional study has been carried out in the Gynecology Discipline, São Paulo University, Brazil, since 2019.
Arq Neuropsiquiatr
September 2025
Universidade de São Paulo, Faculdade de Medicina, Departamento de Fisioterapia, Fonoaudiologia e Terapia Ocupacional, São Paulo SP, Brazil.
Williams syndrome (WS) is a genetic, multisystemic, and neurodevelopmental disorder. The prevalence of auditory hypersensitivity in WS is high, especially in childhood, with reports in the literature from 94 to 100% of individuals evaluated, which can generate significant impacts on their quality of life. Therefore, the existence of instruments for screening hyperacusis that are easy and quick to apply for use in clinical routine is essential.
View Article and Find Full Text PDFRev Esc Enferm USP
September 2025
Universidade Estadual Paulista, Faculdade de Medicina, Botucatu, SP, Brazil.
Objective: To evaluate the effectiveness of intravenous laser irradiation of blood in reducing viral load and increasing LT-CD4+ and LT-CD8+ in people living with HIV/AIDS.
Method: Randomized, controlled, parallel, single-blind clinical trial. Twenty-eight participants were allocated to the intervention (ILIB n = 15) and control (CTRL n = 13) groups.
Front Psychol
August 2025
Tokyo College, The University of Tokyo, Tokyo, Japan.
Introduction: Excessive and compulsive behaviors, including substance and behavioral addictions, represent a growing global concern. In Brazil, the increasing prevalence of these behaviors underscores the need for effective screening tools to identify individuals at risk. The Brief Screener for Substance and Behavioral Addiction (SSBA) has been recognized internationally for its utility in both clinical assessment and public health surveillance.
View Article and Find Full Text PDFJ Bras Nefrol
September 2025
Sociedade Brasileira de Nefrologia, São Paulo, SP, Brazil.
Brazil ranks among the top five countries performing kidney transplants, operating the largest public transplantation system in the world. Nevertheless, the number of procedures performed represents less than 40% of demand, and there are significant regional disparities, with areas of the country reporting very low transplantation activity. Among the potential causes of this scenario are the low frequency of referrals for transplant evaluation and referrals made under inappropriate clinical conditions.
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