Publications by authors named "Nelson Wolosker"

Objective: Analyze the trends and outcomes of total laryngectomy in Brazil, focusing on the influence of surgical volume on mortality.

Methods: A retrospective, population-based study was conducted using data from the Brazilian Unified Health System (SUS) between 2008 and 2023. Total laryngectomies were identified through specific procedure codes, and hospitals were categorized into quartiles based on surgical volume.

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Background: The use of long-term devices for chemotherapy in neoplastic diseases is very common. The CAVA trial was an extensive study that prospectively evaluated more than 1000 patients undergoing chemotherapy and randomly allocated them to three groups based on the type of catheters used: peripherally inserted central catheters, Port, or Hickmann. For this study, the Quality of Life Vascular Access Device (QoLVAD) questionnaire was administered to assess the impact of these devices (abovementioned catheters) on the patients' daily lives.

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This randomized cross-over study examined the acute effects of single-task or dual-task walking physical activity (PA) breaks of prolonged sitting among healthy older adults on cognitive performance and cerebral blood flow velocity (CBFv). Twenty-seven healthy older adults (69.4 ± 5.

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Background: Physical activity (PA) is recognized as a protective factor against depressive symptoms; however, the role of different PA patterns remains unclear. This study aimed to investigate the association between the "weekend warrior" PA pattern and depressive symptoms in the Brazilian population, with analyses stratified by sex and obesity status.

Methods: This cross-sectional study analyzed data from 29,907 individuals aged 18 and older who underwent screening exams between 2008 and 2022 at a Brazilian hospital.

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Purpose: Exercises with a self-selected intensity (SSI) have emerged as an alternative to guideline-recommended sessions to improve adherence to exercise programs. We compared the cardiovascular and perceptual responses during a walking exercise performed at SSI and in a session with intensity recommended by clinical guidelines.

Methods: Twenty patients (mean 69.

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Objective: To examine the association between the weekend warrior physical activity pattern and erectile dysfunction, including analyses stratified by age group and obesity.

Methods: Data from 15,655 men aged >40 screened at a Brazilian hospital (2008-2022) were analyzed. Physical activity was assessed using the International Physical Activity Questionnaire.

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Background: The treatment of thoracoabdominal aortic aneurysms (TAA) has advanced. Understanding the pathophysiology and surgical approaches to this disease is essential for best therapeutic performance.

Objectives: We aimed to improve previously described methods for creating thoracoabdominal aortic aneurysms in a porcine animal model, reducing surgical procedure time and specimen mortality.

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Objective: To evaluate the relationship between the absorbed dose and radiological response in patients with hepatocellular carcinoma undergoing resin microsphere radioembolization to enhance treatment precision and potentially adjust protocols for better outcomes.

Methods: This single-center retrospective study was conducted at a quaternary care center in Brazil and comprised 27 patients with 58 target lesions treated between November 2014 and April 2023. The patients' dosimetric profiles were analyzed using advanced imaging software to assess post-treatment clinical and radiological responses.

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Objective: Venous thromboembolism is a condition of great interest to public health, as it is potentially preventable and has a high morbidity and mortality potential. Knowing the real-world data in a country of continental dimensions such as Brazil is essential to help define health policies that enable proper diagnosis and treatment of this disease. The objective of this study was to evaluate the incidence and in-hospital mortality rates of venous thromboembolism in public hospitals under Brazil's public health system.

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Background: This study evaluated the association between changes in physical activity and depression among 1,950 Brazilians. Individuals who increased their physical activity and those who decreased it were not associated with reduced depression. Conversely, being consistently active was identified as an independent and significant protective factor against depression in this population.

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Background: Calcium scores were evaluated in the lower limbs of patients with clinical limb ischemia after aortoiliac revascularization. The aortic calcium score was related to the short-term outcomes of amputation and subsequent revascularization. Similarly, the calcium score in below-the-knee arteries was associated with revascularization and amputation at 12 months.

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Background: Patients with symptomatic peripheral artery disease (PAD) face numerous barriers to engaging in physical activity (PA), such as exercise-induced pain, so it is reasonable to hypothesize that these patients do not like engaging in PA. Therefore, this study aimed to analyze the prevalence of self-reported like engaging in PA, as well as whether this factor is associated with higher levels of PA and lower sedentary behavior (SB) in patients with symptomatic PAD.

Methods: This cross-sectional study included 178 patients with symptomatic PAD who were submitted to a question related to self-reported like engaging in PA and a questionnaire related personal and environmental barriers to PA.

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Background: Amputations in children represent significant events. Few studies analyse amputations in this specific population, and most of them are old, regionalised and with small sample sizes. Besides, there are no large studies in low-income and middle-income countries.

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Spontaneous non-aneurysmal aortic rupture is rare and is usually attributed to penetrating aortic ulcers, infections, tumor infiltrations, or inflammatory and collagen diseases. Chronic rupture is infrequent but extremely rare in non-aneurysmal aortas, which makes diagnosis difficult because the absence of an aneurysm can mislead the physician to rule out rupture. Here, we describe the case of an 85-year-old male, who was undergoing oncological investigation for weight loss, inappetence, and back pain.

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Objective: This study aimed to evaluate the association between physical activity levels and lower urinary tract symptoms in 20,732 Brazilian men.

Methods: This cohort study included 20,732 men of ≥40 years of age, who participated in health screening between January 2008 and December 2018. Standardized health data (anthropometric, laboratory, clinical, and lifestyle data) were collected.

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Objective: This study aimed to investigate the relationship between depression and erectile dysfunction while controlling for sociodemographic, physical health, psychological, and lifestyle factors. Additionally, it aimed to compare erectile dysfunction with other clinical, laboratory, and behavioral variables among individuals with depression in the same population.

Methods: We included 21,139 men (≥40 years) who underwent continuous health screening in a quaternary hospital in São Paulo between January 2008 and December 2018.

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Objective: This study tests a suitable model for training robot-assisted peripheral vascular interventions and examines the learning curves of endovascular surgeons with different levels of previous experience and main focus of work, analyzing procedure time, fluoroscopy time, use of contrast, and radiation emission.

Methods: Sixteen endovascular surgeons with different previous experience and training performed nine manual and 18 robotic angioplasties using the CorPath GRX platform on a 3D-printed life-size immersed infragenicular arterial phantom.

Results: All participants considered the model reliable.

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Article Synopsis
  • The study aimed to objectively assess sweat intensity in patients with primary hyperhidrosis by measuring their electrodermal activity without external prompts.
  • Researchers compared two groups: 10 patients suffering from palmoplantar hyperhidrosis and 10 control individuals, evaluating their sweat perception and mental health through questionnaires and measuring electrodermal activity with a portable device.
  • Results showed that patients with hyperhidrosis had significantly higher palmoplantar sweating and skin conductance compared to controls, but no notable differences in anxiety or depression levels between the groups, confirming the effectiveness of the non-invasive measuring technique.
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Objective: Identify potential negative impacts arising from implementing an electronic medical record system, classify them according to the level of criticality, and analyze method's effectiveness after implementation.

Methods: The research involved identifying the negative impacts, classifying them according to the criteria for criticality, stratifying them as high, medium, or low severity, and finally, analyzing the effectiveness of the identification and classification methods.

Results: Findings confirmed that 89.

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Objective: To evaluate the incidence of malfunction and colonization rates of fully implantable long-term catheters left unflushed during the COVID-19 pandemic; and to evaluate the average cost of transporting each patient to the hospital for flushing.

Methods: During the COVID-19 pandemic, patients reduced the number of hospital visits and stopped flushing their catheters periodically with saline solution. After the pandemic stabilized in 2022, patients who completed chemotherapy treatment had their long-term catheters removed.

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Purpose: This study aims to evaluate the image quality of computed tomography (CT) angiograms obtained using a virtual contrast augmentation technique, adding an iodine map to the contrast-enhanced images, obtained through a digital subtraction technique, reducing the dose of intravenous iodinated contrast medium compared to the conventional institutional standard technique.

Methods: This prospective investigation enrolled patients previously diagnosed with abdominal aortic aneurysms, who underwent two successive computed tomography angiographies (CTAs) of the aorta. One CTA was performed employing the virtual contrast enhancement boost technique with a 40% decrease in the intravenous contrast medium dose, while the other adhered to the conventional protocol without any reduction in contrast medium volume.

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A 42-year-old female patient with a surgical history of iliac venous angioplasty with stenting developed dyspnea on exertion 9 months later. Chest computed tomography angiography revealed a fractured vascular stent in the right cardiac chamber. Doppler echocardiography confirmed that the stent was anchored by the tricuspid valve, causing mild obstruction of the right ventricular filling.

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Objectives: To analyze and compare, in an animal model, the treatment of thoracoabdominal aneurysms with multilayer stents and its hemodynamic effects through the biomechanical and histological analysis of the aortic wall in contact with the stent.

Methods: Large White pigs were randomized into two groups: Stent (n=6) and Control (n=5, non-stent). All animals were subjected to the creation of a suprarenal aneurysm with a bovine pericardial patch.

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Purpose: This study investigated whether: 1) walking training (WT) changes cardiovascular load after walking until maximal intermittent claudication (IC) in patients with peripheral artery disease (PAD); and 2) acute and chronic cardiovascular responses to walking were related to each other.

Methods: A randomized, controlled, parallel-group design was employed. Thirty-two men with PAD and IC were randomly assigned to one of two groups: WT (n=16) or control (CO, n=16) twice a week for 12 weeks.

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Background: We examined the sedentary behavior and physical activity of 260 patients with peripheral artery disease. Women engaged in more light physical activity than men did. Light physical activity was associated with lower arterial stiffness in men only, while no significant associations were found between sedentary behavior, moderate-vigorous physical activity, and cardiovascular outcomes.

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