Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Quantum optical coherence tomography (QOCT) is the non-classical counterpart of optical coherence tomography (OCT), by which quantum interference of entangled photon pairs is used to show some advantages over classical OCT. Currently, almost all research on the QOCT focuses on the case with two photons and a twofold improvement in axial resolution has been demonstrated. Here, we introduce the multiple reflections strategy into the QOCT scheme, referencing the multi-pass strategy of the sequential scheme in quantum metrology, and provide a theoretical framework for multi-reflection quantum-optical coherence tomography (MQOCT). According to such a scheme, when the incident light interacts with the sample times, the axial resolution of MQOCT is theoretically enhanced by a factor of compared to that of QOCT under the same spectral bandwidth while preserving the dispersion cancellation capability of QOCT. Furthermore, we present a classical optical analogy of MQOCT using -beam correlated multi-mode broadband beams and experimentally validate it. The classical optical analogy of MQOCT theoretically has the same resolution enhancement capability and dispersion cancellation capability as MQOCT while avoiding the fragility issues associated with the quantum light source which is used in MQOCT.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1364/OE.551731 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Multimodal Deep Learning for Predicting Postoperative Vault and Selecting ICL Sizes Using AS-OCT and UBM Images.
J Cataract Refract Surg
July 2025
Department of Ophthalmology, West China Hospital of Sichuan University, Chengdu City, Sichuan Province, China.
Purpose: To develop and validate a multimodal deep-learning model for predicting postoperative vault height and selecting implantable collamer lens (ICL) sizes using Anterior Segment Optical Coherence Tomography (AS-OCT) and Ultrasound Biomicroscope (UBM) images combined with clinical features.
Setting: West China Hospital of Sichuan University, China.
Design: Deep-learning study.
A randomized, double-blind, placebo-controlled phase 1 trial of the topical pan-lysyl oxidase inhibitor PXS-6302 in mature scars.
Sci Transl Med
September 2025
Burn Injury Research Unit, School of Biomedical Sciences, University of Western Australia, Perth, Western Australia 6009, Australia.
Skin scars remain a substantial clinical challenge because of their impact on appearance and psychological well-being. Lysyl oxidases catalyze collagen cross-linking, a key factor in scar development. Here, we report a randomized, double-blind, placebo-controlled phase 1 study to assess the safety and tolerability of PXS-6302, a topical pan-lysyl oxidase inhibitor, in treating mature scars (ACTRN12621001545853).
View Article and Find Full Text PDFMediTEDNet: Visual State Space Model for Thyroid Eye Disease Classification.
IEEE J Biomed Health Inform
September 2025
Thyroid eye disease (TED) is a prevalent autoimmune orbital disorder that can severely impair visual function and significantly diminish patients' quality of life. In recent years, several studies have attempted to automate TED diagnosis using optical coherence tomography (OCT) images. However, existing approaches primarily rely on convolutional neural networks (CNNs) combined with attention mechanisms and are mostly trained using traditional cross-entropy loss.
View Article and Find Full Text PDFQuantifying tumour microvasculature with optical coherence angiography and intravoxel incoherent motion diffusion MRI.
IEEE Trans Med Imaging
September 2025
Intravoxel Incoherent Motion (IVIM) MRI is a contrast-agent-free microvascular imaging method finding increasing use in biomedicine. However, there is uncertainty in the ability of IVIM-MRI to quantify tissue microvasculature given MRI's limited spatial resolution (mm scale). Nine NRG mice were subcutaneously inoculated with human pancreatic cancer BxPC-3 cells transfected with DsRed, and MR-compatible plastic window chambers were surgically installed in the dorsal skinfold.
View Article and Find Full Text PDFQuantification of Normative Human Choriocapillaris Measures Across the Macula.
Invest Ophthalmol Vis Sci
September 2025
Division of Biomedical Physics, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, Maryland, United States.
Purpose: To assess macular choriocapillaris (CC) metrics in healthy volunteers (HVs) without ocular disease and demonstrate CC variations in patients with inherited retinal dystrophies (IRDs) using adaptive optics optical coherence tomography angiography (AO-OCTA).
Methods: Twenty-one HVs and three IRD patients were imaged. Macular variation in 20 HVs in CC metrics (CC density, CC diameter, CC tortuosity, void diameter, void area, lobule count, lobule area, and RPE-CC distance) were assessed by imaging a 28° strip of overlapping AO-OCTA volumes (3° × 3°) from the optic nerve head to the temporal macula.