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This work presents a characterization study on the internal quantum efficiency of InGaN-based green light-emitting diodes (LEDs) grown on Si with a markedly different buffer strain. One with a huge residual compressive strain but a low density of threading dislocations (TDD, ∼9.0 × 10cm) by using the conventional Al-composition step-graded AlN/AlGaN buffer, and the other nearly strain-free but with a relatively high TDD (∼2.5 × 10cm) by using an AlN single-layer buffer. An intriguing difference in internal quantum efficiency of 56% and 78% for the two samples is revealed. By combining temperature-dependent and time-resolved photoluminescence studies to modify the classical Arrhenius formula, it is evident that the strain relaxation of multiple quantum wells can generate a substantial amount of defects. Moreover, the radiative and non-radiative recombination efficiency as a function of excitation power is extracted according to the ABC model by performing the power-dependent photoluminescence characterization. Finally, a possible model for the carrier recombination dynamics of the InGaN-based green LEDs grown on Si under a low (below 100 µW, < 10cm) to high excitation (above 10 mW,>10cm) is proposed.
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http://dx.doi.org/10.1364/OE.546537 | DOI Listing |
Mol Divers
September 2025
Department of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, 11942, Al Kharj, Saudi Arabia.
Cyclin-dependent kinase 20 (CDK20), also known as cell cycle-related kinase (CCRK), plays a pivotal role in hepatocellular carcinoma (HCC) progression by regulating β-catenin signaling and promoting uncontrolled proliferation. Despite its emerging significance, selective small-molecule inhibitors of CDK20 remain unexplored. In this study, a known CDK20 inhibitor, ISM042-2-048, was employed as a reference to retrieve structurally similar compounds from the PubChem database using an 85% similarity threshold.
View Article and Find Full Text PDFMed Phys
September 2025
Department of Radiology, Keio University School of Medicine, Tokyo, Japan.
Background: Understanding respiratory motions of liver and its surrogate organs is crucial for precise dose delivery in liver cancer radiotherapy. Although these motions have been studied for respiratory motion management in the supine posture, few studies have quantified them and evaluated their correlations in the upright posture.
Purpose: This study quantified the respiratory motions of liver and surrogate organs and evaluated the correlations between the liver motions and surrogate signals for respiratory motion monitoring in both the supine and upright postures.
J Phys Chem Lett
September 2025
School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, U.K.
The electron-deficient oxidant 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) has recently emerged as a promising visible-light photoredox catalyst. However, its excited-state behavior remains poorly understood. Here, we investigate the ultrafast dynamics of photoexcited DDQ in acetonitrile using transient electronic and infrared absorption spectroscopy, supported by quantum chemical calculations.
View Article and Find Full Text PDFRedox Biol
September 2025
Multi-Omics Platform, Center for Cancer Immunotherapy and Immunobiology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Human Biology Microbiome Quantum Research Center, Keio University School of Medicine, Tokyo, Japan. Electronic address:
Ferroptosis, an iron-dependent cell death mechanism characterized by excessive lipid peroxidation, has been implicated in numerous human diseases and organ pathologies. However, current detection methods necessitate invasive tissue sampling to assess lipid peroxidation, making noninvasive detection of ferroptosis in human subjects extremely challenging. In this study, we employed oxidative volatolomics to comprehensively characterize the volatile oxidized lipids (VOLs) produced during ferroptosis.
View Article and Find Full Text PDFAnal Chim Acta
November 2025
Institute of Materials Science, Vietnam Academy of Science and Technology, Hanoi, 10000, Viet Nam. Electronic address:
Background: Recent advancements in cancer therapeutics have catalyzed the development of noninvasive treatment modalities, including the utilization of fluorescent chemotherapeutic agents. These agents offer dual functionality, enabling targeted drug delivery, real-time tumor imaging, and personalized therapy monitoring. Such capabilities are instrumental in the progression toward more precise and effective cancer interventions.
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