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Background: Dry beans and chickpeas are nutritionally valuable legumes widely consumed worldwide. This study examines the impact of oven roasting (110 °C for 70 min) on the phytochemical, antioxidant, fatty acid and saponin profiles of 12 pulses, including 11 common beans and 1 chickpea.
Results: Roasting significantly affected the phytochemical composition and antinutritional factors with distinct variations among samples. Cranberry bean CRAN-1 exhibited the highest total phenolic content in raw samples (19.12 g kg GAE g DW), which decreased by 6.79% post-roasting. Pigmented beans including dark red kidney and CRAN-2 showed strong antioxidant activities pre-roasting (DPPH scavenging: 73.94% and 50.16%, respectively). CRAN-2 also had the highest anthocyanin content (0.057 to 0.036 g kg DW) among pigmented cultivars, which decreased slightly after roasting. Non-extractable polymeric proanthocyanins remained stable, while saponin content significantly decreased (up to 77% in some cultivars), suggesting improved flavor. Stigmasterol and β-sitosterol were the predominant phytosterols with enhanced availability after roasting. Fatty acid analysis revealed that saturated fatty acids are predominant, ranging from 54.7% (Manteca) to 70% (Great Northern), while the fatty acid composition was similar across all cultivars.
Conclusion: These findings underscore that roasting under mild controlled conditions retains and improves key bioactive compounds in common bean flours. Pigmented varieties, in particular, offer superior antioxidant and phytochemical properties. This research provides a foundation for incorporating roasted pulses into functional formulations with both dietary and industrial applications. © 2025 The Author(s). Journal of the Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
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http://dx.doi.org/10.1002/jsfa.70106 | DOI Listing |
Mol Ther Methods Clin Dev
June 2025
Shanghai Vitalgen BioPharma Co., Ltd., Shanghai 201210, China.
Bietti crystalline dystrophy (BCD) is an autosomal recessive disorder caused by loss-of-function mutations in the gene, characterized by crystal-like lipid deposits in the retina, progressive photoreceptor loss, and retinal pigment epithelium (RPE) deterioration. Currently, there are no approved treatments for BCD. VGR-R01, an investigational gene therapy, uses subretinal administration of recombinant adeno-associated virus type 8 (AAV8) vector to deliver the human CYP4V2 gene.
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September 2025
Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo 7-3-1 Hongo, Bunkyo-ku Tokyo 113-8656 Japan
Polyunsaturated fatty acids (PUFAs), fatty acids with multiple unsaturated carbon-carbon bonds, constitute a crucial class of lipids. While the vast diversity of PUFA species arises from their structural variations, most of them are poorly investigated due to their limited availability. Here, we utilize solid-phase synthesis of PUFAs, which we have recently developed, to construct a PUFA library.
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August 2025
Hans Merensky Chair in Avocado Research, University of Pretoria, Pretoria, South Africa.
Phytophthora root rot caused by the hemibiotrophic oomycete, is a major biotic hindrance in meeting the ever-increasing demand for avocados. In addition, the pathogen is a global menace to agriculture, horticulture and forestry. Phosphite trunk injections and foliar sprays remain the most effective chemical management strategy used in commercial avocado orchards against the pathogen.
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August 2025
Department of Animal Science - Texas A&M University, College Station, TX 77843, USA.
This experiment evaluated the effects of supplementing yeast culture ( ) on in situ ruminal degradability, rumen fermentation and microbiota responses of heifers consuming a forage-based diet. Twelve ruminally-cannulated Angus-influenced heifers were ranked by body weight ( 180 ± 4 kg) and assigned to 4 groups of 3 heifers each. Groups were enrolled in a replicated 3 × 3 Latin square design containing 3 periods of 21 d and 14-d washout intervals.
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August 2025
Conservative Dentistry and Endodontics, AB Shetty Memorial Institute of Dental Sciences, Nitte (deemed to be) University, Mangalore, India.
Short-chain fatty acids (SCFAs), primarily acetate (C2), propionate (C3), and butyrate (C4), are crucial microbial metabolites formed by the fermentation of dietary fibers by gut microbiota in the colon. These SCFAs, characterized by fewer than six carbon atoms, serve as an essential energy source for colonic epithelial cells and contribute approximately 10% of the body's total energy requirement. They are central to maintaining gut health through multiple mechanisms, including reinforcing intestinal barrier function, exerting anti-inflammatory effects, regulating glucose and lipid metabolism, and influencing host immune responses.
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