98%
921
2 minutes
20
We report the case of a very rare instance of congenital corneal anesthesia secondary to brainstem lesions following neonatal hypoxic-ischemic encephalopathy. It's the case of a 7-month-old baby with a history of neonatal asphyxia who presented with spontaneous corneal ulcerations and corneal anesthesia associated with brainstem lesions and brain lesions visible on MRI, secondary to neonatal hypoxic-ischemic encephalopathy. The case of the baby was complicated by the superinfection of the ulceration. He was treated with fortified antibiotics, eyedrops, and frequent instillation of eye lubricants and ointments. The evolution was marked by the healing of the ulceration and the improvement of the corneal sensitivity; however, there were sequelae in the more affected eye by the formation of a corneal pannus.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12338002 | PMC |
http://dx.doi.org/10.7759/cureus.87777 | DOI Listing |
Unlabelled: Contact lens wear in humans and mice is consistently associated with asymptomatic corneal parainflammation. Here, we tested the hypothesis that the corneal response to lens wear alone can function to protect it against bacterial adhesion enabled by superficial injury. One eye only of mT/mG-LysMcre mice (cell membranes red; Lyz2 cells green) wore a contact lens for 4-6 days.
View Article and Find Full Text PDFEye (Lond)
September 2025
Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, ON, Canada.
Background/objectives: FACE-Q Craniofacial Module is a validated patient-reported outcome measure for appearance. This study aimed to assess the content validity of FACE-Q Craniofacial Module for use in patients treated for corneal anaesthesia.
Subjects/methods: This was a qualitative, prospective observational study.
Life (Basel)
August 2025
Department of Ophthalmology, School of Medicine, University of Mostar, 88 000 Mostar, Bosnia and Herzegovina.
Background: Obstructive sleep apnea (OSA) is increasingly recognized as a potential risk factor for glaucoma due to its association with intermittent hypoxia and vascular dysregulation. The aim of this study was to investigate early glaucomatous changes in the eyes of patients with OSA.
Methods: This case-control study included 25 patients with OSA and 25 age- and sex-matched healthy controls.
Indian J Ophthalmol
September 2025
Department of Ophthalmology, Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
This study aimed to assess the interchangeability of pachymetry measurements obtained by anterior segment optical coherence tomography (AS-OCT) and ultrasound biomicroscopy (UBM) in children with congenital corneal opacity (CCO). In this single-centre, comparative case series, children with unilateral or bilateral CCO who underwent examination under anesthesia (EUA) were evaluated using both AS-OCT and UBM. Pachymetry values from both modalities were compared using Bland-Altman analysis, and topography maps from AS-OCT were examined.
View Article and Find Full Text PDFEquine Vet J
August 2025
Unit for Ophthalmology, Centre for Veterinary Clinical Services, School of Veterinary Medicine, Freie Universität Berlin, Berlin, Germany.
Background: Retrobulbar anaesthesia (RBA) is relevant for ocular surgery in standing sedated horses.
Objectives: Gathering insights on experiences with RBA techniques.
Study Design: Cross-sectional survey.