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Purpose: Notions of trust are foundational to competency-based medical education. "Entrustability" underlies assessment; assessment is guided by integration into curricula of learners' knowledge, skills, and attitudes. However, attitudinal notions of trust are not commonly conceptualized as integral to such frameworks. Overlap between concepts of entrustability and trust as an attitude creates opportunity to infuse trust into competency frameworks. We explored how an original bedside cardiac assessment (BCA) curriculum that supported professional attitudes, knowledge, and skills scaffolded clinical learning in a cohort of internal medicine clerkship students.
Methods: The curriculum urged students to hear patients' perspectives with humility and as key to diagnostic reasoning. Assigned short videos preceded two facilitated classes that included discussing a patient's startling question, "Why should I trust your clinical skills?" and recognizing, in simulated clinical encounters, disparate patients' perspectives. To better understand their experiences, we asked sixty-seven students to complete two post-class open-ended questions. We analyzed responses using content and thematic analyses.
Results: Emergent codes clustered around themes in two categories: "Successful Learning" around effective learning strategies and meaningful peer encounters, skills practice, and educator encounters; and "Opportunities for Improvement", around instructional design, learning preferences, and instruction-related improvements.
Conclusion: Themes suggested effective learning and meaningful interactions. Comments affirmed the importance of attitudinal aspects of skills development; human interaction while learning; and humility, a linchpin of expertise development and patient-centered communication. All contribute to professional identity formation (PIF). Instructional design improvements were incorporated into the final version of the curriculum. Limitations included inability to examine nuances of emergent themes from the limited data set. We are studying the curriculum's effects on BCA-related knowledge, skills, and attitudes and trust-worthiness as a learning construct. Research opportunities include impacts on humility, patient-centeredness, and PIF. We hope this exploratory work will stimulate conversations around expanded roles of notions of trust in medical education.
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http://dx.doi.org/10.2147/AMEP.S520398 | DOI Listing |
Eur J Heart Fail
September 2025
School of Cardiovascular & Metabolic Medicine and Science, James Black Centre, King's College London British Heart Foundation Centre of Excellence, London, UK.
Aims: Skeletal muscle energetic augmentation might be a mechanism via which intravenous iron improves symptoms in heart failure, but no direct measurement of intrinsic mitochondrial function has been performed to support this notion. This molecular substudy of the FERRIC-HF II trial tested the hypothesis that ferric derisomaltose (FDI) would improve electron transport chain activity, given its high dependence on iron-sulfur clusters which facilitate electron transfer during oxidative phosphorylation.
Methods And Results: Vastus lateralis skeletal muscle biopsies were taken before and 2 weeks after randomization.
Neurology
September 2025
Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, United Kingdom.
Background And Objectives: Cerebrovascular reactivity (CVR) is an indicator of cerebrovascular health, and its signature in familial frontotemporal dementia (FTD) remains unknown. The primary aim was to investigate CVR in genetic FTD using an fMRI index of vascular contractility termed resting-state fluctuation amplitudes (RSFAs) and to assess whether RSFA differences are moderated by age. A secondary aim was to study the relationship between RSFA and cognition.
View Article and Find Full Text PDFGenome Biol
September 2025
Department of Archaeology and Museology, Masaryk University, Brno, Czech Republic.
Background: The Slavs are a major ethnolinguistic group of Europe, yet the process that led to their formation remains disputed. As of the sixth century CE, people supposedly belonging to the Slavs populated the space between the Avar Khaganate in the Carpathian Basin, the Merovingian Frankish Empire to the West and the Balkan Peninsula to the South. Proposed theories to explain those events are, however, conceptually incompatible, as some invoke major population movements while others stress the continuity of local populations.
View Article and Find Full Text PDFThe procedural account of prison legitimacy proposes that inmates' compliance with correctional institutions depends more on whether they feel that prison guards treat them fairly during their daily interactions than on whether the guards' decisions are ultimately favourable to them. In , Anthony Bottoms and Alison Liebling provide a compelling overview of their work in this area, highlighting the importance of respectful relationships for building feelings of trust in penal institutions and advancing a humanitarian account of legitimacy that is sensitive to the moral and relational dimensions of order maintenance. Despite their important contribution, Bottoms and Liebling's procedural approach advances a precarious notion of legitimacy that depends too heavily on the fair treatment of inmates by prison guards and too little on methods of inmate participation that might help the institution align its values with those of prisoners, creating a more stable, and truly normative, commitment towards compliance.
View Article and Find Full Text PDFJAMA Cardiol
August 2025
German Centre for Cardiovascular Research Partner Site North, Hamburg/Kiel/Lübeck, Germany.
Importance: Mounting evidence suggests transcatheter aortic valve implantation (TAVI) as preferred treatment for patients at low to intermediate surgical risk. However, limitations in study design and statistical power raise concerns about the generalizability of individual randomized clinical trials (RCTs) comparing TAVI and surgical aortic valve replacement (SAVR) to routine clinical practice.
Objective: To compare 1-year outcomes of TAVI vs SAVR in patients with severe symptomatic aortic stenosis at low to intermediate surgical risk applying a 2-stage individual participant data (IPD) and aggregate meta-analyses.