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Purpose: To evaluate the feasibility of applying a barium enema-style bowel preparation protocol to CT colonography (CTC) in clinical practice.
Materials And Methods: 11 patients underwent CTC using a simplified bowel preparation protocol based on magnesium citrate, similar to that used for barium enema. Two radiologists assessed the homogeneity of fluid tagging, volume of residual fluid, and degree of colonic distension in six colonic segments (cecum, ascending, transverse, descending, sigmoid, rectum) in both supine and prone positions. Each parameter was rated on a 4-point Likert scale (0 = optimal, 3 = inadequate). The mean score and proportion of segments achieving a score of 0 were calculated.
Results: More than 85% of segments received a score of 0 for tagging uniformity and colonic distension, and over 90% for residual fluid. Mean scores were below 0.3 for all three parameters. These findings indicate that the preparation protocol provided sufficient colonic cleansing and distension comparable to previously reported standard protocols.
Conclusion: A simplified bowel preparation protocol adapted from barium enema practice can be effectively applied to CT colonography, achieving clinically acceptable image quality.
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http://dx.doi.org/10.1007/s11604-025-01848-9 | DOI Listing |
Eur J Neurosci
September 2025
The Tampa Human Neurophysiology Lab, Department of Neurosurgery, Brain and Spine, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.
Sensory areas exhibit modular selectivity to stimuli, but they can also respond to features outside of their basic modality. Several studies have shown cross-modal plastic modifications between visual and auditory cortices; however, the exact mechanisms of these modifications are yet not completely known. To this aim, we investigated the effect of 12 min of visual versus sound adaptation (referring to forceful application of an optimal/nonoptimal stimulus to a neuron[s] under observation) on the infragranular and supragranular primary visual neurons (V1) of the cat (Felis catus).
View Article and Find Full Text PDFJ Forensic Leg Med
August 2025
Laboratory of Criminalistics, Adam Mickiewicz University in Poznań, al. Niepodległości 53, Poznań 61-714, Poland; Center for Advanced Technologies, Adam Mickiewicz University in Poznań, ul. Uniwersytetu Poznańskiego 10, Poznań 61-614, Poland.
This study examines the reliability of fingerprint experts in assessing the individualization value of minutiae during the analysis of latent fingerprint traces. Despite the widespread use of fingerprint evidence in criminal investigations, growing concerns about examiner variability and the lack of verification protocols have prompted critical scrutiny of forensic practices. In this study, 30 Polish fingerprint experts were asked to identify and evaluate seven minutiae in two fingerprint traces of differing quality.
View Article and Find Full Text PDFJ Histotechnol
September 2025
3d.FAB, Université Claude Bernard Lyon 1, CNRS, INSA, CPE-Lyon, Villeurbanne, France.
Histological preparation paraffin embedding is the gold standard method for evaluating tissue structure and composition, whether it is originated from biopsy or engineered . Quite often, deformation and shrinkage occur during the histological preparation, which are difficult to predict and qualify. The present study investigates the morphometric changes in bioprinted hydrogels composed of alginate and gelatine, common tissue engineering materials, focusing on three morphologies: full slabs, porous slabs, and porous cubes.
View Article and Find Full Text PDFDiabetologia
September 2025
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.
Aims/hypothesis: Alpha cell dysregulation is an integral part of type 2 diabetes pathophysiology, increasing fasting as well as postprandial glucose concentrations. Alpha cell dysregulation occurs in tandem with the development of insulin resistance and changes in beta cell function. Our aim was to investigate, using mathematical modelling, the role of alpha cell dysregulation in beta cell compensatory insulin secretion and subsequent failure in the progression from normoglycaemia to type 2 diabetes defined by ADA criteria.
View Article and Find Full Text PDFOrg Lett
September 2025
National Key Laboratory of Advanced Drug Delivery and Release Systems, School of Pharmaceutical Sciences & Institute of Materia Medica, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250117, P. R. China.
A method for the conversion of isoxazoles into thiazoles by skeleton rearrangement has been achieved by an ammonium iodide-catalyzed cycloaddition protocol under mild conditions with a broad substrate scope and good functional group tolerance. Most appealingly, the reaction can proceed smoothly without the addition of any transition metal catalyst. Detailed mechanistic studies, including control experiments and key reaction intermediate characterization, reveal an intermolecular [3+2] cycloaddition reaction pathway.
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