Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Breast cancer (BC) is a kind of cancer that is created from the cells in breast tissue. This is a primary cancer that occurs in women. Earlier identification of BC is significant in the treatment process. To lessen unwanted biopsies, Magnetic Resonance Imaging (MRI) is utilized for diagnosing BC nowadays. MRI is the most recommended examination to detect and monitor BC and explain lesion areas as it has a better ability for soft tissue imaging. Even though, it is a time-consuming procedure and requires skilled radiologists. Here, Breast Cancer Deep Convolutional Neural Network (BCDCNN) is presented for Breast Cancer Detection (BCD) using MRI images. At first, the input image is taken from the database and subjected to a pre-processing segment. Adaptive Kalman filter (AKF) is utilized to execute the pre-processing phase. Thereafter, cancer area segmentation is conducted on filtered images by Pyramid Scene Parsing Network (PSPNet). To improve segmentation accuracy and adapt to complex tumor boundaries, PSPNet is optimized using the Jellyfish Search Optimizer (JSO). It is a recent nature-inspired metaheuristic that converges to an optimal solution in fewer iterations compared to conventional methods. Then, image augmentation is performed that includes augmentation techniques namely rotation, random erasing and slipping. Afterwards, feature extraction is done and finally, BCD is conducted employing BCDCNN, wherein the loss function is newly designed based on an adaptive error similarity. It improves the overall performance by dynamically emphasizing samples with ambiguous predictions, enabling the model to focus more on diagnostically challenging cases and enhancing its discriminative capability. Furthermore, BCDCNN acquired 90.2% of accuracy, 90.6% of sensitivity and 90.9% of specificity. The proposed method not only demonstrates strong classification performance but also holds promising potential for real-world clinical application in early and accurate breast cancer diagnosis.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12334629PMC
http://dx.doi.org/10.1038/s41598-025-09974-0DOI Listing

Publication Analysis

Top Keywords

breast cancer
24
cancer
9
cancer deep
8
deep convolutional
8
convolutional neural
8
neural network
8
cancer detection
8
mri images
8
breast
6
bcdcnn
4

Similar Publications

Chemotherapeutic resistance is a significant issue in the treatment of breast cancer, which is related to pyroptosis inhibition. Increasing evidence suggests that long non-coding RNAs (lncRNAs) contribute to tumorigenesis and drug resistance. In this study we investigated the role of the lncRNA STMN1P2 in doxorubicin resistance in breast cancer, as well as its correlation with pyroptosis inhibition.

View Article and Find Full Text PDF

Comprehensive genomic profiling (CGP) expands treatment options for solid tumor patients and identifies hereditary cancers. However, in Japan, confirmatory tests have been conducted in only 31.6% of patients with presumed germline pathogenic variants (GPVs) detected through tumor-only testing.

View Article and Find Full Text PDF

Purpose: Recent advancements in medical technologies have made trans-arterial treatment of breast cancer feasible. Consequently, understanding the vascular anatomies of breast cancers and axillary lymph node metastases has become indispensable for sophisticated treatments. The aim of this study was to determine the vascular anatomy of the breast, which is crucial for trans-arterial chemoembolization in patients with breast cancer.

View Article and Find Full Text PDF