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Introduction: Puberty health, as a fundamental aspect of adolescent health, requires targeted and evaluated educational programs. However, to date, a comprehensive tool to measure the effectiveness of these programs has not been developed. Therefore, this study aimed at the design and psychometric validation of the Evaluation Scale for Puberty Health Education Programs (EPHEP-Scale) for students aged 10-18.
Method: To develop and validate this scale, a sequential exploratory mixed-methods design was used. The samples included 850 students aged 10 to 18 from four Arab countries. The study also utilized Exploratory Graph Analysis (EGA) from a network perspective.
Results: The results of the EFA and CFA showed that this scale includes six factors: Behavioral Reflexivity in Health Practices, Cognitive Resonance with Puberty, Transformative Impact on Self and Aspirations, Interpersonal Connectivity and Social Navigation, Emotional Synchrony and Adaptation, and Meta-Cognition and Reflective Learning. Additionally, network analysis further supported the six-factor structure of the EPHEP. These results indicate that the EPHEP-Scale is an accurate and reliable tool for evaluating puberty health education programs, making it suitable for use in various educational settings.
Implications For School Health Policy, Practice, And Equity: The EPHEP-Scale offers policymakers and school health practitioners a culturally validated, equity-focused tool to assess and refine puberty health curricula. By capturing psychosocial and behavioral dimensions, it enables targeted resource allocation, particularly in resource-limited or culturally diverse settings, and promotes equitable evaluation of program impacts across gender and regional contexts. Adoption of this instrument can support data-driven policy decisions to enhance access, reduce stigma, and ensure that all students benefit from high-quality, contextually relevant puberty education.
Conclusion: By providing a comprehensive framework to measure multiple aspects of puberty health development, the EPHEP enhances the effectiveness of these programs and enables their optimization for diverse student groups. With its broad impact on the design and implementation of educational initiatives, this scale plays a crucial role in improving the quality of life of puberties, as well as their mental and social well-being, ultimately fostering healthier and more informed generations across different communities.
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http://dx.doi.org/10.1111/josh.70060 | DOI Listing |
Dev Psychobiol
September 2025
School of Psychology, UNSW Sydney, Sydney, New South Wales, Australia.
Adolescent male rodents and humans exhibit impairments in extinguishing learned fear. Here, we investigated whether female adolescent rats exhibit such impairments and if extinction is affected by the estrous cycle as in adults. Following fear conditioning to a discrete cue, female adolescent Sprague Dawley rats were extinguished either around the onset of puberty, when estrous cycling begins, or across different stages of the estrous cycle.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
September 2025
Department of Endocrinology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310052, China.
The onset of puberty is increasingly observed at earlier ages in children, especially in girls with obesity, a trend that predisposes them to long-term metabolic and reproductive disorders in adulthood. Bile acids have emerged as pivotal signaling molecules in both metabolic and reproductive disorders, but remain unexplored in the early onset of puberty in children. Herein, we find elevated levels of muricholic acid (MCA) species in the serum of girls with central precocious puberty, which strongly correlate with indices of hypothalamic-pituitary-gonadal axis activation and can reach peak levels during puberty among healthy children.
View Article and Find Full Text PDFAnn Pediatr Endocrinol Metab
August 2025
Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Purpose: Although insulin resistance (IR) varies with age and puberty in children and adolescents, most previous attempts to determine cutoff values for IR indices overlook factor. This study assesses age-related differences in IR index values and evaluates how diagnostic performance varies by age when using a uniform cutoff for diagnosing metabolic syndrome (MetS) without considering age.
Methods: We analyzed age-related differences in IR indices (the homeostatic model assessment of insulin resistance [HOMA-IR], triglyceride-glucose [TyG] index, and triglyceride/high-density lipoprotein cholesterol [TG/HDL-C] ratio) among 1,641 participants in the 2019-2021 Korea National Health and Nutrition Examination Survey.
J Affect Disord
September 2025
Department of Public Health, Bartholins Allé 2, Aarhus University, 8000, Aarhus C, Denmark. Electronic address:
Purpose: To study the association between internalizing and externalizing symptoms and prosocial behavior at age 7 years and pubertal timing in boys and girls.
Methods: This cohort study included 11,090 children from the Puberty Cohort within the Danish National Birth Cohort (DNBC). Data on internalizing and externalizing symptoms and prosocial behavior was derived from a parent-reported Strengths and Difficulties Questionnaire (SDQ) at age 7 years, and categorized as normal (lowest 79th percent), at-risk (80th - 89th percent) or abnormal (≥90th percent).
Epigenomics
September 2025
McGill Group for Suicide Studies, Douglas Mental Health University Institute, Montreal, Canada.
DNA methylation (DNAm) is a key epigenetic modification that dynamically regulates eukaryotic development over time. DNAm has been found to influence a variety of biological processes in both normative and pathological states, such as depression. Since DNAm can serve as an interface between environmental influence and gene expression, it is a mechanism studied in the context of many pathologies, including psychiatric.
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