Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Iodomethane is a commonly used methylation reagent in organic synthesis. However, reports of acute iodomethane poisoning are rare. Herein, we report the successful treatment of a patient with acute iodomethane poisoning. During processing and production, owing to inadequate personal protection, the patient's eyes were directly exposed to iodomethane gas, leading to blurred vision and magnetic resonance imaging findings consistent with toxic encephalopathy. Following a comprehensive diagnosis and treatment at our hospital, outpatient follow-ups and clinical assessments confirmed the patient's recovery.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12325289 | PMC |
| http://dx.doi.org/10.3389/fphar.2025.1574692 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Case Report: A case of occupational methyl iodide-induced encephalopathy.
Front Pharmacol
July 2025
Department of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Iodomethane is a commonly used methylation reagent in organic synthesis. However, reports of acute iodomethane poisoning are rare. Herein, we report the successful treatment of a patient with acute iodomethane poisoning.
View Article and Find Full Text PDFMRI Spectrum of Toxic Encephalopathy-An Institutional Experience.
Neurol India
September 2022
Department of Neuroimaging and Interventional Radiology, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, Karnataka, India.
Background: There are numerous toxins that affect our nervous system, both central and peripheral. Innumerable differentials exist in patients of acute encephalopathy and the list can be narrowed down with appropriate imaging. Specific neuroradiological features point to a particular diagnosis in a substantial number of cases.
View Article and Find Full Text PDFA Model of Human Small Airway on a Chip for Studies of Subacute Effects of Inhalation Toxicants.
Toxicol Sci
May 2022
Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas 77843, USA.
Testing for acute inhalation hazards is conducted in animals; however, a number of robust in vitro human cell-based alternatives have been developed and tested. These models range in complexity from cultures of cell lines or primary cells in air-liquid interface on Transwells, to more complex and physiologically relevant flow- and mechanical stimulation-enabled tissue chips. Although the former models are relatively straightforward to establish and can be tested in medium/high throughput, the latter require specialized equipment and lack in throughput.
View Article and Find Full Text PDFDevelopment of an in vitro approach to point-of-contact inhalation toxicity testing of volatile compounds, using organotypic culture and air-liquid interface exposure.
Toxicol In Vitro
December 2020
ScitoVation, LLC, Durham, NC 27713, United States. Electronic address:
In vitro chemical risk assessment using human cells is emerging as an alternative to in vivo animal testing with reduced costs, fewer animal welfare concerns, and the possibility of greater human health relevance. In vitro inhalation toxicity testing of volatile compounds poses particular challenges. Here we report our efforts to establish a testing protocol in our own lab using the EpiAirway bronchial epithelium cell culture model and the Vitrocell 12/12 system for air-liquid interface (ALI) exposures.
View Article and Find Full Text PDFSensing Living Bacteria Using d-Alanine-Derived C Radiotracers.
ACS Cent Sci
February 2020
Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.
Incorporation of d-amino acids into peptidoglycan is a unique metabolic feature of bacteria. Since d-amino acids are not metabolic substrates in most mammalian tissues, this difference can be exploited to detect living bacteria . Given the prevalence of d-alanine in peptidoglycan muropeptides, as well as its role in several antibiotic mechanisms, we targeted this amino acid for positron emission tomography (PET) radiotracer development.
View Article and Find Full Text PDF