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Objectives: More than one-third of discharged emergency department (ED) patients leave without a clear diagnosis for their symptoms. In 2019-2020, we implemented a simulation-based mastery learning curriculum across two academic medical centers to train emergency medicine residents to discuss diagnostic uncertainty during ED discharge, guided by the Uncertainty Communication Checklist (UCC). We sought to assess if this cohort continues to apply skills learned and to obtain trainee insights into the most valuable checklist items.
Methods: A survey was emailed to all 109 participants who completed the training in 2019-2020. Questions assessed how often participants currently encountered uncertainty and used the skills learned in the curriculum. Additionally, participants rated how important it was to keep each of the 21 UCC items in future uncertainty communication training (4-point Likert scale: very important/important/low importance/not important). Means and proportions are reported.
Results: Sixty-five individuals responded (60%). Mean age was 33; and 30.8% were female. More than 90% encountered diagnostic uncertainty more than once per shift, and 74% applied skills learned in the training "often" or "all the time." Seven of the 21 UCC items received endorsement by more than 70% of respondents as "very important" to retain in future trainings. The item receiving the most endorsement as "very important" (90%) was to "Clearly state that either 'life-threatening' or 'dangerous' conditions have not been found." Items with lower rankings related to generally accepted communication best-practices (e.g., "make eye contact").
Conclusion: Four years following diagnostic uncertainty training completion, most respondents frequently employ skills learned from uncertainty communication training.
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http://dx.doi.org/10.1002/aet2.70086 | DOI Listing |
Br J Cancer
September 2025
Centre for Cancer Screening, Prevention and Early Diagnosis, Wolfson Institute of Population Health, Queen Mary University of London, London, E1 1HH, UK.
Background: Multi-cancer detection (MCED) blood tests have the potential to screen for early-stage cancers. Understanding how people experience an MCED cancer signal result is vital prior to any future implementation. We explored experiences in a trial context.
View Article and Find Full Text PDFReprod Biomed Online
May 2025
Department of Obstetrics and Gynaecology, and Neonatology, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Centre for Obstetrics and Gynaecology, Guangdong-Hong Kong-Macao Greater Bay Area Higher Education Joint Laboratory of Maternal-Fetal Med
Research Question: What is the global, regional and national burden of polycystic ovary syndrome (PCOS), particularly in adolescents, based on data from the Global Burden of Disease (GBD) 2021 study?
Design: Prevalence, incidence and years lived with disability (YLD) for PCOS were extracted from the GBD 2021 database, standardized via Bayesian meta-regression, and stratified by age, region and Socio-Demographic Index (SDI). Temporal trends (1990-2021) were presented, and future projections (to 2045) were modelled using autoregressive integrated moving average models.
Results: Between 1990 and 2021, the global prevalence of PCOS increased from 36.
PLoS One
September 2025
Department of Maths and Computer Science, Faculty of Science, University of Kinshasa, Kinshasa, The Democratic Republic of the Congo.
Reliable and timely fault diagnosis is critical for the safe and efficient operation of industrial systems. However, conventional diagnostic methods often struggle to handle uncertainties, vague data, and interdependent multi-criteria parameters, which can lead to incomplete or inaccurate results. Existing techniques are limited in their ability to manage hierarchical decision structures and overlapping information under real-world conditions.
View Article and Find Full Text PDFPLoS One
September 2025
Wake Forest University School of Medicine, Department of Implementation Science, Winston-Salem, North Carolina, United States of America.
Background: Hepatitis C virus (HCV) and injection drug use among young women are dramatically rising in the rural United States. From 2004 to 2017, heroin use among non-pregnant women increased 22.4% biennially, mirroring increases in HCV cases, especially among younger populations.
View Article and Find Full Text PDFCereb Cortex
August 2025
Department of Developmental Psychology, University of Amsterdam, Nieuwe Achtergracht 129b, 1018 WS Amsterdam, The Netherlands.
Social learning, a hallmark of human behavior, entails integrating other's actions or ideas with one's own. While it can accelerate the learning process by circumventing slow and costly individual trial-and-error learning, its effectiveness depends on knowing when and whose information to use. In this study, we explored how individuals use social information based on their own and others' levels of uncertainty.
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