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Collagen IV, a key structural protein of basement membranes, is vital for the development and survival of multicellular life forms. Its maturation relies on specific post-translational O- glycosylation, primarily mediated by lysyl hydroxylase-3 (LH3) and other glycosyltransferases, which sculpt collagen by modifying the hydroxylysine residues with sugar moieties.
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http://dx.doi.org/10.1038/s41467-025-62768-w | DOI Listing |
Nat Commun
August 2025
School of Biosciences and Bioengineering, Indian Institute of Technology (IIT) Mandi, Mandi, Himachal Pradesh, India.
Collagen IV, a key structural protein of basement membranes, is vital for the development and survival of multicellular life forms. Its maturation relies on specific post-translational O- glycosylation, primarily mediated by lysyl hydroxylase-3 (LH3) and other glycosyltransferases, which sculpt collagen by modifying the hydroxylysine residues with sugar moieties.
View Article and Find Full Text PDFVox Sang
August 2008
Faculty of Pharmaceutical Sciences, Tokyo University of Sciences, Yamazaki, Noda, Chiba, Japan.
Background And Objectives: Enzymatic treatment of red blood cells is thought to reduce the cell zeta (zeta) potential, effectively decreasing the distance between cells to less than the length of an immunoglobulin G antibody binding site, and resulting in agglutination of cells. However, the zeta potential given by Smoluchowski's formula is based on theories of the electrophoresis of hard colloidal particles. A theory has recently been developed for the electrophoresis of colloidal particles covered with polyelectrolytes, which we call 'soft particles'.
View Article and Find Full Text PDFAppl Microbiol Biotechnol
May 2001
Abteilung für Technische Mykologie, Institut für Forstbotanik de Universität Göttingen, Germany.
The cell walls of woody plants are compounded materials made by in situ polymerization of a polyphenolic matrix (lignin) into a web of fibers (cellulose), a process that is catalysed by polyphenoloxidases (laccases) or peroxidases. The first attempt to transform the basic strategy of this natural process for use in human craftsmanship was the ancient lacquer method. The sap of the lacquer tree (Rhus verniciflua) contains large amounts of a phenol (urushiol), a polysaccharide and the enzyme laccase.
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