Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Disorders of the respiratory muscles (RM) are common, yet are often overlooked. Physical examination findings may suggest the presence of RM weakness but are nonspecific. Several tests of RM function are available, including measurements of upright and supine vital capacity, inspiratory and expiratory muscle pressures, sniff nasal inspiratory pressure, sniff esophageal and transdiaphragmatic pressures, and peak cough flow. These tests are widely available but are effort dependent. Electrodiagnostic studies, such as electromyography, electrical, or magnetic phrenic nerve stimulation, are effort independent but require more specialized equipment and staff. Imaging techniques such as ultrasound provide helpful complementary information about diaphragm function.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ccm.2025.04.013 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Protective Role of Apelin in a Mouse Model of Post-Intensive Care Syndrome.
Am J Respir Cell Mol Biol
September 2025
University of Toronto, Interdepartmental Division of Critical Care Medicine, Toronto, Ontario, Canada.
Post-Intensive Care Syndrome (PICS) is a serious condition involving physical weakness, depression, and cognitive impairment that develop during or after an intensive care unit (ICU) stay, often resulting in long-term declines in quality of life. Patients with acute respiratory distress syndrome (ARDS) and severe COVID-19 are at particularly high risk, yet the molecular mechanisms underlying PICS remain poorly understood. Here, we identify impaired Apelin-APJ signaling as a potential contributor to PICS pathogenesis via disruption of inter-organ homeostasis.
View Article and Find Full Text PDFPulmonary Function in Early-Onset Scoliosis: A Literature Review.
JBJS Rev
September 2025
Seattle Children's Hospital, Seattle, Washington.
» Early-onset scoliosis (EOS) causes restrictive lung disease, secondary to deformation of the thoracic cavity, stiffening of the chest wall, and weakening of the respiratory muscles.» Early spinal fusion has been shown to limit thoracic growth and be associated with poor pulmonary outcomes. This has led to the rise of growth-friendly surgical techniques to maximize thoracic growth.
View Article and Find Full Text PDFAn Indirect Treatment Comparison of Avalglucosidase Alfa versus Cipaglucosidase Alfa Plus Miglustat in Patients with Late-Onset Pompe Disease.
Adv Ther
September 2025
Sanofi, Gentilly, France.
Introduction: No head-to-head studies comparing the efficacy of avalglucosidase alfa (AVA) with cipaglucosidase alfa + miglustat (Cipa+mig) have been conducted in patients with late-onset Pompe disease (LOPD). Two indirect treatment comparisons (ITCs) were conducted to estimate the effects of AVA versus Cipa+mig.
Methods: ITCs were conducted using simulated treatment comparisons (STCs), adjusting for differences in prognostic factors and treatment effect modifiers.
The Role of Worry and Affectivity on Physiological Responses To an Acute Stressor.
Appl Psychophysiol Biofeedback
September 2025
Florida State University, Tallahassee, USA.
The explanation for how acutely stressful experiences could result in proximal health outcomes has been lacking in occupational health research. Although scholars have argued that individual personality and affect could worsen health behaviors, we believe that these qualities also could intensify the experience of acute stressors, potentially explaining why acutely stress encounters result in poor health outcomes for some people, but not others. Our study examines three individual differences - worry, negative affect, and positive affect - that are relevant to differential stress anticipation, reactivity, and recovery.
View Article and Find Full Text PDFAbdominal Compartment Syndrome Following Endovascular Aneurysm Repair for Ruptured Abdominal Aortic Aneurysm: A Challenging Case.
Surg Case Rep
August 2025
Department of Vascular Surgery, Asahikawa Medical University, Asahikawa, Hokkaido, Japan.
Introduction: Abdominal compartment syndrome (ACS) is a serious complication that can occur after endovascular aneurysm repair (EVAR) for ruptured abdominal aortic aneurysm (rAAA). Prompt recognition and appropriate management are crucial to improve patient outcomes.
Case Presentation: An octogenarian with an 11-cm rAAA underwent emergent EVAR due to cardiovascular instability.