Benign Duodenal Leiomyoma Mimicking Malignancy on 68Ga-FAPI PET/CT.

Clin Nucl Med

Departments of Nuclear Medicine, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia, People's Republic of China.

Published: August 2025


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Article Abstract

We present PET/CT findings of a 62-year-old woman with duodenal leiomyoma. 18F-FDG PET/CT demonstrated a mass with mild FDG uptake at the duodenal papilla (SUVmax, 3.7). 68Ga-FAPI PET/CT showed intense FAPI uptake in the same region (SUVmax, 9.6). These imaging findings raised suspicion for malignancy. However, histopathologic examination revealed duodenal leiomyoma. This case highlights that benign duodenal leiomyoma should be included in the differential diagnosis of duodenal FAPI-avid malignant lesions.

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http://dx.doi.org/10.1097/RLU.0000000000006094DOI Listing

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