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We present PET/CT findings of a 62-year-old woman with duodenal leiomyoma. 18F-FDG PET/CT demonstrated a mass with mild FDG uptake at the duodenal papilla (SUVmax, 3.7). 68Ga-FAPI PET/CT showed intense FAPI uptake in the same region (SUVmax, 9.6). These imaging findings raised suspicion for malignancy. However, histopathologic examination revealed duodenal leiomyoma. This case highlights that benign duodenal leiomyoma should be included in the differential diagnosis of duodenal FAPI-avid malignant lesions.
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http://dx.doi.org/10.1097/RLU.0000000000006094 | DOI Listing |
Clin Nucl Med
August 2025
Departments of Nuclear Medicine, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia, People's Republic of China.
We present PET/CT findings of a 62-year-old woman with duodenal leiomyoma. 18F-FDG PET/CT demonstrated a mass with mild FDG uptake at the duodenal papilla (SUVmax, 3.7).
View Article and Find Full Text PDFInt J Surg Case Rep
August 2025
Department of Surgery, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia. Electronic address:
Introduction And Importance: Duodenal leiomyomas are rare, often asymptomatic benign tumors, typically discovered incidentally during surgery. This case highlights a unique leiomyoma found during robotic Single Anastomosis Duodeno-Ileal bypass (SADI), emphasizing the importance of intraoperative adaptability in bariatric surgery.
Case Presentation: A 56-year-old male with a BMI of 56 kg/m underwent robotic SADI.
Case Rep Gastroenterol
March 2025
Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Introduction: Esophageal leiomyomas are relatively common benign esophageal submucosal tumors (SMTs). Generally, benign tumors do not accumulate fluorine-18-fluorodeoxyglucose (FDG), but it is not rare for FDG to accumulate in uterine, duodenal, or esophageal leiomyomas. In our case, we performed peroral endoscopic tumor resection (POET) for an esophageal leiomyoma with FDG accumulation.
View Article and Find Full Text PDFInt J Surg Case Rep
August 2025
Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan.
Introduction: Duodenal leiomyomas are rare mesenchymal tumors. To date, several studies have reported on the safety and feasibility of surgical intervention for duodenal leiomyomas. However, minimally invasive surgery has rarely been performed in cases with duodenal leiomyomas.
View Article and Find Full Text PDFEndocr Pract
March 2025
Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Department of Medicine, Mayo Clinic, Rochester, Minnesota.
Objective: This document presents the findings of the American Association of Clinical Endocrinology (AACE) on the diagnosis, management, and surveillance of patients with multiple endocrine neoplasia type 1 (MEN1) and associated tumors. The task force included a diverse group of experts in endocrinology, oncology, genetics, surgery, and patient representation. A comprehensive literature review was conducted to address key issues related to the evaluation, surveillance, and treatment of MEN1-related tumors.
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