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Introduction: Outcome uncertainty is known to engage motivational and emotional phenomena. However, there remain questions as to how outcome uncertainty related to gain and loss and information availability via performance feedback interact to impact motivational and emotional phenomena: (1) generally, and (2) in relation to individual differences in intolerance of uncertainty, and current symptoms related to anxiety and depression.
Methods: To address these gaps in the literature, we manipulated the level of outcome uncertainty (gain, loss, none) and performance feedback (present, absent) during an online cognitive control task ( = 69), to examine how these factors impact different read-outs: subjective emotional responses (valence, arousal), task accuracy, reaction times, and fixation count. Self-reported intolerance of uncertainty and symptoms of general distress, anxious arousal, and anhedonic depression were also collected.
Results: Outcome uncertainty related to loss and gain, compared to no outcome, was associated with higher arousal and higher task accuracy. Uncertainty about task performance through the absence of performance feedback lowered arousal, dampened positive affect, and led to demotivation (i.e. lowered task accuracy and fixation count). Individual differences in intolerance of uncertainty and symptoms of anxiety and depression were specifically associated with different self-reported experiences of emotion (i.e. valence) and motivational engagement (i.e. fixation count).
Discussion: These findings suggest that outcome uncertainty and performance feedback, as well as intolerance of uncertainty, and anxious/depressive traits differently impact motivation and emotion.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12314322 | PMC |
http://dx.doi.org/10.3389/fpsyg.2025.1469701 | DOI Listing |
BJOG
September 2025
Department of Obstetrics and Gynaecology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Objective: To estimate the effect on healthcare resource use after introducing the World Health Organization diagnostic criteria (WHO-2013) for gestational diabetes mellitus (GDM) compared to former criteria in Sweden (SWE-GDM).
Design: A cost-analysis alongside the Changing Diagnostic Criteria for Gestational Diabetes (CDC4G) randomised controlled trial.
Setting: Sweden, with risk-factor based screening for GDM.
Sports Med
September 2025
Aspetar Orthopaedic and Sports Medicine Hospital, FIFA Medical Centre of Excellence, Doha, Qatar.
Sports injury surveillance programs have been vital in advancing the understanding of injury epidemiology across various athlete populations. Surveillance-based epidemiological measures of injury occurrence are ubiquitous in the sports medicine literature, and the injury rate is one such commonly used measure. Traditional approaches to calculating injury rates have predominantly relied on frequentist methods, which, while informative, have limitations in addressing certain practical questions.
View Article and Find Full Text PDFBMJ Open
September 2025
School of Exercise and Health, Shanghai University of Sport, Shanghai, China
Introduction: Although emerging evidence supports the short-term efficacy of transcranial magnetic stimulation (TMS), including repetitive TMS (rTMS) and theta-burst transcranial magnetic stimulation (TBS-TMS), and transcranial direct current stimulation (tDCS) for managing patients with chronic musculoskeletal pain (CMP), their clinical utility in managing CMP remains inconclusive. This uncertainty may arise from methodological limitations, including heterogeneity in treatment parameters such as stimulation targets and dosages. Additionally, safety profiles for these non-invasive brain stimulation interventions in patients with CMP remain insufficiently reported, with limited data on adverse events, cumulative risks and long-term safety outcomes.
View Article and Find Full Text PDFJ Thorac Oncol
September 2025
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea; Emeritus Professor, Seoul National University College of Medicine, Seoul, Republic of Korea.
Introduction: Multifocal subsolid nodules (SSNs) are increasingly detected with widespread lung cancer screening and advanced thoracic imaging, representing a spectrum of multifocal lung adenocarcinomas (LUADs). When synchronous SSNs coexist with a surgically confirmed subsolid LUAD, their trajectories remain poorly understood, contributing to uncertainty regarding optimal management strategies. This study aimed to evaluate the clinical course and impact of synchronous SSNs in such patients and to identify features associated with their progression.
View Article and Find Full Text PDFEur J Obstet Gynecol Reprod Biol
September 2025
Department of Obstetrics and Gynecology, Zhongda Hospital, Southeast University, Nanjing, Jiangsu, China. Electronic address:
Background: Ectopic pregnancy (EP) represents a leading cause of maternal mortality in early gestation and a significant contributor to future reproductive impairment. Comprehensive understanding of global EP epidemiological patterns and their temporal evolution is crucial for developing holistic strategies to promote health equity and optimize allocation of medical resources worldwide.
Methods: Leveraging Global Burden of Disease (GBD) 2021 data, this investigation systematically examined age-standardized rates (ASRs) of EP incidence, prevalence, mortality, and disability-adjusted life years (DALYs) across 204 countries and 21 regions from 1990 to 2021.