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Introduction: Patient reported experience measures (PREMs) are important tools to include the voices of patients in healthcare provision. Children have a right to be included in decisions made about their care. A self-reported, locally validated and standardised paediatric PREM (pPREM) does not exist for use in Australian healthcare settings. Further, existing pPREMs are rarely codesigned with children or developed to be completed by children themselves. This study aims to validate a pPREM that will be completed by children within Australian healthcare settings.
Methods And Analysis: This study will involve three subphases, engaging children aged 6-11 years old who have had a hospital admission in the past 3 months. First, up to 25 children will participate in cognitive interviews to pilot test pPREM items. Using feedback from the interviews, population testing will occur with about 180 children at six Australian hospitals to determine the validity, reliability and feasibility of the pPREM. The study's implementation process will be evaluated through interviews with approximately 25-30 clinicians, managers and other stakeholders.
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http://dx.doi.org/10.1136/bmjpo-2025-003490 | DOI Listing |
Thromb Res
September 2025
Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University, Mainz, Germany. Electronic address:
Warfarin is a widely used vitamin K antagonist (VKA) with known pleiotropic effects beyond anticoagulation. Preclinical and case-control evidence suggests that warfarin may affect hematopoiesis, but longitudinal human evidence is lacking. To explore this potential effect, we conducted a post-hoc analysis of participants in the Hokusai-VTE and ENGAGE AF-TIMI 48 trials, which randomized patients to warfarin or the direct oral anticoagulant edoxaban with routine laboratory testing at predefined follow-up visits.
View Article and Find Full Text PDFBiomaterials
August 2025
Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, 90095, USA. Electronic address:
Wearable bioelectronics have transformed modern biomedical applications by enabling seamless integration with biological tissues, providing continuous, comprehensive, and personalized healthcare. Skin cancer, particularly melanoma, poses a significant clinical challenge due to its high metastatic potential and associated mortality. Traditional diagnostic approaches face limitations in accuracy, accessibility, and reproducibility, while existing treatments are often constrained by systemic toxicity and therapeutic resistance.
View Article and Find Full Text PDFInt J Law Psychiatry
September 2025
Child and Adolescent Psychiatry, Department of Medical Sciences, Uppsala University, Uppsala, Sweden; Child Study Center, Yale School of Medicine, New Haven, CT, USA; Regional forensic psychiatric clinic Sala, Sala, Sweden. Electronic address:
In many countries little is known about the attitudes and ethical beliefs of practicing psychiatrists towards the use of coercive practices. This is true as regards Russia where coercion was used for political purposes during the Soviet period. However, substantial changes have occurred in the psychiatric system in recent decades with a focus on patients' rights and the idea of consent.
View Article and Find Full Text PDFTurk J Pediatr
September 2025
Division of Allergy and Asthma, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Türkiye.
Animal allergens, particularly those from cats, dogs, and horses, are significant risk factors for the development of allergic diseases in childhood. Managing animal allergies requires allergen avoidance and, when this is not feasible, specific immunotherapy. Patient history remains the cornerstone of diagnosis, providing the foundation for diagnostic algorithms.
View Article and Find Full Text PDFTurk J Pediatr
September 2025
Department of Pathology, University of Health Sciences Antalya Education and Research Hospital, Antalya, Türkiye.
Background: Delirium in patients with ulcerative colitis may be seen, especially in the elderly and in patients hospitalized for a long time. In children, Wernicke's encephalopathy may occur due to thiamine deficiency in both ulcerative colitis and Crohn's disease. We present a patient with ulcerative colitis who presented with delirium as the first symptom, did not respond to steroid treatment and improved with anti-tumor necrosis factor-alpha treatment.
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