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Background: Motor impairments, such as motor delays, atypical gait, dyspraxia, and poor coordination, are highly prevalent among individuals with autism spectrum disorder (ASD). Motor impairments are detrimental to multiple aspects of development but are often underdiagnosed and undertreated in children and adolescents with ASD. Child neurologists are specialists who provide clinical care for autistic patients across the lifespan. However, little is known about how child neurologists understand, diagnose, and treat motor impairments in children with ASD.
Methods: In this preliminary study, we surveyed child neurologists (N = 100) on their knowledge of and clinical practices addressing motor impairments in pediatric patients with ASD. Our survey also sought to identify potential barriers to care and medical education efforts that may mitigate existing gaps.
Results: We found most child neurologists were not confident that motor impairments were an associated feature of ASD, do not frequently evaluate for motor impairments, lack sufficient tools for motor evaluations with autistic children, face multiple barriers to providing interventions, and do not receive adequate clinical training regarding this topic.
Conclusions: These preliminary findings suggest that substantial gaps in awareness about motor impairments in ASD persist among practicing child neurologists. Though child neurologists are trained to assess motor function, our results highlight a missed opportunity in the setting of ASD. Child neurologists would benefit from greater attention and resources to learn, evaluate, and treat motor impairments as part of holistic patient care for individuals with ASD.
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http://dx.doi.org/10.1016/j.pediatrneurol.2025.06.025 | DOI Listing |
Alzheimers Res Ther
September 2025
Motor Control and Learning Group, Institute of Human Movement Sciences and Sport, Department of Health Sciences and Technology, ETH Zurich, Leopold-Ruzicka-Weg 4, Zurich, 8093, Switzerland.
World Neurosurg
September 2025
Department of Spinal Surgery, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland. Electronic address:
Background: Spinal cord perfusion impairment is a critical secondary mechanism in acute spinal cord injury (SCI). Although lumbar cerebrospinal fluid (CSF) drainage is widely used in cardiothoracic surgery, its use in SCI remains limited. This study presents an evaluation of the safety and feasibility of lumbar CSF drainage with intrathecal pressure (ITP) and spinal cord perfusion pressure (SCPP) monitoring in acute SCI patients.
View Article and Find Full Text PDFNeurotoxicology
September 2025
Laboratory of Pharmacology of Inflammation and Behavioral (LAFICO), Health Science Institute, Federal University of Pará, Belém 66075110, PA, Brazil. Electronic address:
Ketamine has been widely used as a recreational substance by adolescents and young adults in nightclubs and raves in an acute manner, especially during the weekend. Considering the scarcity of evidence on the harmful consequences of adolescent ketamine recreational use on the central nervous system, primarily related to motor function, this study aimed to investigate the behavioral, biochemical, and neurochemical consequences on motor function induced by ketamine use, evaluating the motor cortex, cerebellum, and striatum in early abstinence. Adolescent female Wistar rats (28 days old) received ketamine by intranasal route (10mg/kg/day) for 3 consecutive days.
View Article and Find Full Text PDFJ Physiol
September 2025
Department of Human Nutrition, Foods, and Exercise, Virginia Tech, Blacksburg, Virginia, USA.
Cognitive decline and physical impairment are often linked with ageing, contributing to declines in health span and loss of independence in older adults. Pathological cognitive decline with age is largely considered to be a brain-centric challenge. However, recent findings have begun to challenge this paradigm as the health of peripheral systems, namely skeletal muscle, predict cognitive decline associated with Alzheimer's disease (AD).
View Article and Find Full Text PDFNeurosci Bull
September 2025
Zhejiang Key Laboratory of Organ Development and Regeneration, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou, 311121, China.
The neurological manifestations of SHORT syndrome include intrauterine growth restriction, microcephaly, intellectual disability, hearing loss, and speech delay. SHORT syndrome is generally believed to be caused by PIK3R1 gene mutations and impaired PI3K-AKT activation. Recently, a clinical case report described a SHORT syndrome with a novel mutant in PRKCE gene encoding protein kinase Cε (PKCε).
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