Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Aseptic loosening remains a main complication following total knee arthroplasty (TKA), requiring revision surgery. Radiostereometric analysis (RSA) can assess the risk of aseptic loosening. This study evaluated the migration and segmental motion of cemented and uncemented femoral and asymmetrical tibial Persona components (Zimmer Biomet) with model-based RSA.
Methods: We conducted a randomized controlled trial with 63 patients (22 male patients and 41 female patients, with a mean age of 62 years) and compared patients who underwent TKA with cemented and uncemented Persona components. The primary outcome measure was the maximal total point motion (MTPM) after 2 years. The Mann-Whitney U test was used to compare groups. Migration was visualized by plotting the mean and 95% confidence interval (CI).
Results: After 3 months, femoral components demonstrated an MTPM of 0.41 mm (95% CI, 0.35 to 0.48 mm) in the cemented group and 0.65 mm (95% CI, 0.50 to 0.80 mm) in the uncemented group. Subsequently, a stabilization occurred, and the MTPM after 24 months was 0.51 mm (95% CI, 0.41 to 0.61 mm) in the cemented group and 0.83 mm (95% CI, 0.65 to 1.02 mm) in the uncemented group. There was a significant difference between fixation types at 3 months (p = 0.04), 6 months (p = 0.03), 12 months (p = 0.02), and 24 months (p = 0.02). At 3 months postoperatively, the tibial component demonstrated an MTPM of 0.70 mm (95% CI, 0.53 to 0.88 mm) in the cemented group and 0.76 mm (95% CI, 0.61 to 0.91 mm) in the uncemented group. A stabilization was then observed, and migration after 24 months was 0.72 mm (95% CI, 0.55 to 0.89 mm) for cemented components and 0.78 mm (95% CI, 0.64 to 0.92) for uncemented components.
Conclusions: TKA with cemented and uncemented Persona components showed migration values within acceptable ranges, suggesting successful long-term fixation; however, significant differences in mean MTPM between cemented and uncemented femoral components were found.
Level Of Evidence: Therapeutic Level I . See Instructions for Authors for a complete description of levels of evidence.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.2106/JBJS.24.00835 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Functional Outcomes in Failed Osteosynthesis of Proximal Femoral Fractures Managed by Total Hip Replacement Using the Modified Hardinge Approach: An Ambispective Cohort Study.
Cureus
August 2025
Department of Orthopaedic Surgery, King George's Medical University, Lucknow, IND.
Introduction Proximal femoral fractures are a major cause of disability, particularly in aging populations, with an increasing incidence. Although osteosynthesis remains the first-line treatment, failures are common due to various complications. Total hip arthroplasty (THA) is the preferred salvage procedure in such cases, despite its technical challenges.
View Article and Find Full Text PDFRecurrent femoral stem fractures in Dorr A femurs: Lessons learned and a call for alternative strategies.
World J Methodol
December 2025
Centro de Cadera ''Sir John Charnley'' Instituto de Ortopedia y Traumatologia Prof. Dr. Carlos E. Ottolenghi, Hospital Italiano de Buenos Aires, Capital Federal C1198AAW, Buenos Aires, Argentina.
We report a unique case of bilateral femoral stem fractures in a patient with Dorr A femoral morphology, underscoring the need for a critical reassessment of implant selection strategies. The initial failure involved a cemented revision stem placed using the cement-within-cement technique combined with an extended trochanteric osteotomy (ETO). A second revision was subsequently performed using a cortical window osteotomy and a distally fixed uncemented stem, which resulted in successful recovery.
View Article and Find Full Text PDFRadiostereometric Insights into Total Knee Arthroplasty: Cemented and Uncemented Fixation with an Asymmetrical Tibial Component: Commentary on an article by Müjgan Yilmaz Altun, BPT, MD, PhD, et al.: "Migration of Cemented and Uncemented Implants in Total Knee Arthroplasty with an Asymmetrical Tibial Component. A Randomized Controlled Trial with a 2-Year Model-Based Radiostereometric Analysis Follow-up".
J Bone Joint Surg Am
September 2025
Department of Orthopaedic Surgery and Sports Medicine, University of Washington School of Medicine, Seattle, Washington.
Enhanced clinical outcomes of uncemented prostheses in revision surgery of distal femoral tumor prostheses: a retrospective study.
Eur J Med Res
September 2025
Department of Bone Oncology & Diseases Surgery, Department of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Background: The rising incidence of cancer has highlighted the need for effective treatment strategies, particularly for bone tumors like distal femoral tumors. These tumors are among the most prevalent types of bone malignancies, often necessitating extensive surgical intervention to achieve optimal outcomes. Limb-salvage surgery, which involves resecting the tumor and reconstructing the limb with prosthetic devices, has become the standard approach for managing both malignant and aggressive benign tumors of the distal femur.
View Article and Find Full Text PDFPeriprosthetic femoral fracture following hip arthroplasty : which component design and fixation method has the lowest risk of reoperation?
Bone Joint J
September 2025
Norwegian Arthroplasty Register, Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway.
Aims: Periprosthetic femoral fracture (PPFF) is a major complication following hip arthroplasty. This study examined the influence of femoral component design and fixation method on the risk of reoperation for PPFF.
Methods: We analyzed data on femoral component type use for primary hip arthroplasty stems reported to the Norwegian Arthroplasty Register and the Norwegian Hip Fracture Register from 1 January 2005 to 31 December 2023.